Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 7437.066 | 1.0023 | 1.0129 | 0.3525 | |
| HCC1419 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 7437.066 | 0.9994 | 0.9968 | 0.3525 | |
| HCC1419 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 7437.066 | 1.0005 | 1.0029 | 0.3525 | |
| HCC1419 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 7437.066 | 1.0094 | 1.0537 | 0.3525 | |
| HCC1419 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 7437.066 | 0.9598 | 0.7804 | 0.3525 | |
| HCC1419 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 7437.066 | 1.0155 | 1.0893 | 0.3525 | |
| HCC1419 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 7437.066 | 0.9039 | 0.5016 | 0.3525 | |
| HCC1419 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 7437.066 | 0.6842 | -0.3186 | 0.3525 | |
| HCC1419 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7440.066 | 0.9661 | 0.8378 | 0.4073 | |
| HCC1419 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 7440.066 | 0.9744 | 0.8768 | 0.4073 | |
| HCC1419 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 7440.066 | 1.0295 | 1.1481 | 0.4073 | |
| HCC1419 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 7440.066 | 1.0281 | 1.1409 | 0.4073 | |
| HCC1419 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 7440.066 | 1.0232 | 1.1157 | 0.4073 | |
| HCC1419 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 7440.066 | 0.9938 | 0.9698 | 0.4073 | |
| HCC1419 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 7440.066 | 0.9816 | 0.9110 | 0.4073 | |
| HCC1419 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 7440.066 | 1.0009 | 1.0043 | 0.4073 | |
| HCC1419 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 7440.066 | 0.9409 | 0.7221 | 0.4073 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7441.066 | 0.9797 | 0.9468 | 0.7593 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 7441.066 | 0.9888 | 0.9706 | 0.7593 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 7441.066 | 0.9882 | 0.9688 | 0.7593 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 7441.066 | 1.0254 | 1.0672 | 0.7593 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 7441.066 | 0.9764 | 0.9380 | 0.7593 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 7441.066 | 0.9972 | 0.9926 | 0.7593 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 7441.066 | 0.9866 | 0.9647 | 0.7593 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 7441.066 | 0.8430 | 0.5972 | 0.7593 |