Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM229PE | TNBC | - | AG1024 | IGF1R | RTK | 1.33 | uM | 7537.066 | 0.9372 | 0.9379 | 2.0549 | |
| SUM229PE | TNBC | - | AG1024 | IGF1R | RTK | 6.67 | uM | 7537.066 | 0.6967 | 0.6774 | 2.0549 | |
| SUM229PE | TNBC | - | AG1024 | IGF1R | RTK | 33.3 | uM | 7537.066 | 0.5401 | 0.4820 | 2.0549 | |
| SUM52PE | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7539.066 | 0.9888 | 0.9821 | 1.2564 | |
| SUM52PE | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 7539.066 | 0.8701 | 0.7903 | 1.2564 | |
| SUM52PE | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 7539.066 | 0.9490 | 0.9184 | 1.2564 | |
| SUM52PE | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 7539.066 | 0.9827 | 0.9724 | 1.2564 | |
| SUM52PE | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 7539.066 | 0.9304 | 0.8885 | 1.2564 | |
| SUM52PE | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 7539.066 | 0.9150 | 0.8634 | 1.2564 | |
| SUM52PE | HR+ | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 7539.066 | 0.8916 | 0.8254 | 1.2564 | |
| SUM52PE | HR+ | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 7539.066 | 0.5926 | 0.3187 | 1.2564 | |
| SUM52PE | HR+ | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 7539.066 | 0.4716 | 0.0995 | 1.2564 | |
| SUM52PE | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7541.066 | 0.9603 | 0.9449 | 1.4520 | |
| SUM52PE | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 7541.066 | 0.9982 | 0.9975 | 1.4520 | |
| SUM52PE | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 7541.066 | 0.9895 | 0.9854 | 1.4520 | |
| SUM52PE | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 7541.066 | 0.9439 | 0.9220 | 1.4520 | |
| SUM52PE | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 7541.066 | 1.0051 | 1.0070 | 1.4520 | |
| SUM52PE | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 7541.066 | 0.9242 | 0.8943 | 1.4520 | |
| SUM52PE | HR+ | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 7541.066 | 0.9251 | 0.8955 | 1.4520 | |
| SUM52PE | HR+ | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 7541.066 | 0.4522 | 0.1579 | 1.4520 | |
| SUM52PE | HR+ | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 7541.066 | 0.4640 | 0.1786 | 1.4520 | |
| T47D | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7542.066 | 0.9844 | 0.9710 | 1.0766 | |
| T47D | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 7542.066 | 0.9328 | 0.8749 | 1.0766 | |
| T47D | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 7542.066 | 1.0005 | 1.0010 | 1.0766 | |
| T47D | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 7542.066 | 0.9506 | 0.9080 | 1.0766 |