Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
MDA-MB-157
TNBC
Basal B
AG1024
IGF1R
RTK
33.3
uM
7496.066
0.9722 0.9520 1.1616
MDA-MB-157
TNBC
Basal B
AG1024
IGF1R
RTK
0.0000853
uM
7498.066
1.0614 1.1139 1.0752
MDA-MB-157
TNBC
Basal B
AG1024
IGF1R
RTK
0.000427
uM
7498.066
0.9824 0.9672 1.0752
MDA-MB-157
TNBC
Basal B
AG1024
IGF1R
RTK
0.00213
uM
7498.066
1.0369 1.0685 1.0752
MDA-MB-157
TNBC
Basal B
AG1024
IGF1R
RTK
0.0107
uM
7498.066
1.0179 1.0333 1.0752
MDA-MB-157
TNBC
Basal B
AG1024
IGF1R
RTK
0.0533
uM
7498.066
1.0563 1.1045 1.0752
MDA-MB-157
TNBC
Basal B
AG1024
IGF1R
RTK
0.267
uM
7498.066
1.0229 1.0425 1.0752
MDA-MB-157
TNBC
Basal B
AG1024
IGF1R
RTK
1.33
uM
7498.066
0.9908 0.9829 1.0752
MDA-MB-157
TNBC
Basal B
AG1024
IGF1R
RTK
6.67
uM
7498.066
0.9938 0.9884 1.0752
MDA-MB-157
TNBC
Basal B
AG1024
IGF1R
RTK
33.3
uM
7498.066
1.0058 1.0108 1.0752
MDA-MB-175-VII
HR+
Luminal
AG1024
IGF1R
RTK
0.0000853
uM
7499.066
0.9391 0.8473 0.7917
MDA-MB-175-VII
HR+
Luminal
AG1024
IGF1R
RTK
0.000427
uM
7499.066
0.9939 0.9847 0.7917
MDA-MB-175-VII
HR+
Luminal
AG1024
IGF1R
RTK
0.00213
uM
7499.066
1.0196 1.0495 0.7917
MDA-MB-175-VII
HR+
Luminal
AG1024
IGF1R
RTK
0.0107
uM
7499.066
1.0305 1.0773 0.7917
MDA-MB-175-VII
HR+
Luminal
AG1024
IGF1R
RTK
0.0533
uM
7499.066
0.9725 0.9307 0.7917
MDA-MB-175-VII
HR+
Luminal
AG1024
IGF1R
RTK
0.267
uM
7499.066
0.9891 0.9725 0.7917
MDA-MB-175-VII
HR+
Luminal
AG1024
IGF1R
RTK
1.33
uM
7499.066
0.9485 0.8708 0.7917
MDA-MB-175-VII
HR+
Luminal
AG1024
IGF1R
RTK
6.67
uM
7499.066
0.9104 0.7764 0.7917
MDA-MB-175-VII
HR+
Luminal
AG1024
IGF1R
RTK
33.3
uM
7499.066
0.5805 0.0061 0.7917
MDA-MB-175-VII
HR+
Luminal
AG1024
IGF1R
RTK
0.0000853
uM
7500.066
0.9363 0.8382 0.7802
MDA-MB-175-VII
HR+
Luminal
AG1024
IGF1R
RTK
0.000427
uM
7500.066
0.9574 0.8914 0.7802
MDA-MB-175-VII
HR+
Luminal
AG1024
IGF1R
RTK
0.00213
uM
7500.066
0.9181 0.7926 0.7802
MDA-MB-175-VII
HR+
Luminal
AG1024
IGF1R
RTK
0.0107
uM
7500.066
1.0668 1.1729 0.7802
MDA-MB-175-VII
HR+
Luminal
AG1024
IGF1R
RTK
0.0533
uM
7500.066
0.9979 0.9947 0.7802
MDA-MB-175-VII
HR+
Luminal
AG1024
IGF1R
RTK
0.267
uM
7500.066
0.9667 0.9151 0.7802