Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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MDA-MB-157 | TNBC | Basal B | AG1024 | IGF1R | RTK | 33.3 | uM | 7496.066 | 0.9722 | 0.9520 | 1.1616 | |
MDA-MB-157 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7498.066 | 1.0614 | 1.1139 | 1.0752 | |
MDA-MB-157 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.000427 | uM | 7498.066 | 0.9824 | 0.9672 | 1.0752 | |
MDA-MB-157 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.00213 | uM | 7498.066 | 1.0369 | 1.0685 | 1.0752 | |
MDA-MB-157 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0107 | uM | 7498.066 | 1.0179 | 1.0333 | 1.0752 | |
MDA-MB-157 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0533 | uM | 7498.066 | 1.0563 | 1.1045 | 1.0752 | |
MDA-MB-157 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.267 | uM | 7498.066 | 1.0229 | 1.0425 | 1.0752 | |
MDA-MB-157 | TNBC | Basal B | AG1024 | IGF1R | RTK | 1.33 | uM | 7498.066 | 0.9908 | 0.9829 | 1.0752 | |
MDA-MB-157 | TNBC | Basal B | AG1024 | IGF1R | RTK | 6.67 | uM | 7498.066 | 0.9938 | 0.9884 | 1.0752 | |
MDA-MB-157 | TNBC | Basal B | AG1024 | IGF1R | RTK | 33.3 | uM | 7498.066 | 1.0058 | 1.0108 | 1.0752 | |
MDA-MB-175-VII | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7499.066 | 0.9391 | 0.8473 | 0.7917 | |
MDA-MB-175-VII | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 7499.066 | 0.9939 | 0.9847 | 0.7917 | |
MDA-MB-175-VII | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 7499.066 | 1.0196 | 1.0495 | 0.7917 | |
MDA-MB-175-VII | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 7499.066 | 1.0305 | 1.0773 | 0.7917 | |
MDA-MB-175-VII | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 7499.066 | 0.9725 | 0.9307 | 0.7917 | |
MDA-MB-175-VII | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 7499.066 | 0.9891 | 0.9725 | 0.7917 | |
MDA-MB-175-VII | HR+ | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 7499.066 | 0.9485 | 0.8708 | 0.7917 | |
MDA-MB-175-VII | HR+ | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 7499.066 | 0.9104 | 0.7764 | 0.7917 | |
MDA-MB-175-VII | HR+ | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 7499.066 | 0.5805 | 0.0061 | 0.7917 | |
MDA-MB-175-VII | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7500.066 | 0.9363 | 0.8382 | 0.7802 | |
MDA-MB-175-VII | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 7500.066 | 0.9574 | 0.8914 | 0.7802 | |
MDA-MB-175-VII | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 7500.066 | 0.9181 | 0.7926 | 0.7802 | |
MDA-MB-175-VII | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 7500.066 | 1.0668 | 1.1729 | 0.7802 | |
MDA-MB-175-VII | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 7500.066 | 0.9979 | 0.9947 | 0.7802 | |
MDA-MB-175-VII | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 7500.066 | 0.9667 | 0.9151 | 0.7802 |