Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM225CWN | HER2amp | Basal A | AG1024 | IGF1R | RTK | 33.3 | uM | 7533.066 | 0.5730 | 0.0527 | 0.8676 | |
| SUM225CWN | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7534.066 | 0.9982 | 0.9964 | 1.0191 | |
| SUM225CWN | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.000427 | uM | 7534.066 | 1.0010 | 1.0021 | 1.0191 | |
| SUM225CWN | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.00213 | uM | 7534.066 | 0.9804 | 0.9615 | 1.0191 | |
| SUM225CWN | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.0107 | uM | 7534.066 | 1.0827 | 1.1621 | 1.0191 | |
| SUM225CWN | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.0533 | uM | 7534.066 | 0.9796 | 0.9600 | 1.0191 | |
| SUM225CWN | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.267 | uM | 7534.066 | 0.9676 | 0.9363 | 1.0191 | |
| SUM225CWN | HER2amp | Basal A | AG1024 | IGF1R | RTK | 1.33 | uM | 7534.066 | 0.9461 | 0.8942 | 1.0191 | |
| SUM225CWN | HER2amp | Basal A | AG1024 | IGF1R | RTK | 6.67 | uM | 7534.066 | 0.7627 | 0.5332 | 1.0191 | |
| SUM225CWN | HER2amp | Basal A | AG1024 | IGF1R | RTK | 33.3 | uM | 7534.066 | 0.6472 | 0.3051 | 1.0191 | |
| SUM229PE | TNBC | - | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7535.066 | 0.9900 | 0.9744 | 0.7812 | |
| SUM229PE | TNBC | - | AG1024 | IGF1R | RTK | 0.000427 | uM | 7535.066 | 0.9514 | 0.8765 | 0.7812 | |
| SUM229PE | TNBC | - | AG1024 | IGF1R | RTK | 0.00213 | uM | 7535.066 | 0.9878 | 0.9687 | 0.7812 | |
| SUM229PE | TNBC | - | AG1024 | IGF1R | RTK | 0.0107 | uM | 7535.066 | 0.9996 | 0.9989 | 0.7812 | |
| SUM229PE | TNBC | - | AG1024 | IGF1R | RTK | 0.0533 | uM | 7535.066 | 1.0063 | 1.0162 | 0.7812 | |
| SUM229PE | TNBC | - | AG1024 | IGF1R | RTK | 0.267 | uM | 7535.066 | 0.9205 | 0.7988 | 0.7812 | |
| SUM229PE | TNBC | - | AG1024 | IGF1R | RTK | 1.33 | uM | 7535.066 | 1.0144 | 1.0371 | 0.7812 | |
| SUM229PE | TNBC | - | AG1024 | IGF1R | RTK | 6.67 | uM | 7535.066 | 0.7236 | 0.3218 | 0.7812 | |
| SUM229PE | TNBC | - | AG1024 | IGF1R | RTK | 33.3 | uM | 7535.066 | 0.6782 | 0.2165 | 0.7812 | |
| SUM229PE | TNBC | - | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7537.066 | 0.9443 | 0.9450 | 2.0549 | |
| SUM229PE | TNBC | - | AG1024 | IGF1R | RTK | 0.000427 | uM | 7537.066 | 0.9237 | 0.9242 | 2.0549 | |
| SUM229PE | TNBC | - | AG1024 | IGF1R | RTK | 0.00213 | uM | 7537.066 | 0.9730 | 0.9736 | 2.0549 | |
| SUM229PE | TNBC | - | AG1024 | IGF1R | RTK | 0.0107 | uM | 7537.066 | 0.9352 | 0.9359 | 2.0549 | |
| SUM229PE | TNBC | - | AG1024 | IGF1R | RTK | 0.0533 | uM | 7537.066 | 0.9600 | 0.9607 | 2.0549 | |
| SUM229PE | TNBC | - | AG1024 | IGF1R | RTK | 0.267 | uM | 7537.066 | 0.9354 | 0.9361 | 2.0549 |