Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 7818.016 | 0.9374 | 0.8634 | 0.9146 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 7818.016 | 0.9683 | 0.9309 | 0.9146 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 7818.016 | 0.9194 | 0.8244 | 0.9146 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 7818.016 | 0.9445 | 0.8789 | 0.9146 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7818.016 | 0.9563 | 0.9047 | 0.9146 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7818.016 | 0.8259 | 0.6226 | 0.9146 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7818.016 | 0.5562 | 0.0530 | 0.9146 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7818.016 | 0.1807 | -0.6920 | 0.9146 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7818.016 | 0.0334 | -0.9514 | 0.9146 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 7819.016 | 1.0325 | 1.1236 | 0.5331 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 7819.016 | 1.0238 | 1.0904 | 0.5331 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 7819.016 | 1.0096 | 1.0362 | 0.5331 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 7819.016 | 0.9048 | 0.6577 | 0.5331 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7819.016 | 0.9569 | 0.8413 | 0.5331 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7819.016 | 0.8506 | 0.4763 | 0.5331 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7819.016 | 0.5667 | -0.3108 | 0.5331 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7819.016 | 0.2391 | -0.8634 | 0.5331 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7819.016 | 0.3030 | -0.7871 | 0.5331 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 7820.016 | 0.9539 | 0.7996 | 0.4466 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 7820.016 | 0.9505 | 0.7850 | 0.4466 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 7820.016 | 1.0176 | 1.0797 | 0.4466 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 7820.016 | 0.9694 | 0.8656 | 0.4466 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7820.016 | 1.0046 | 1.0207 | 0.4466 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7820.016 | 0.8683 | 0.4578 | 0.4466 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7820.016 | 0.6209 | -0.3120 | 0.4466 |