Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.267 | uM | 7811.044 | 1.0263 | 1.1766 | 0.3073 | |
| HCC1187 | TNBC | Basal A | AG1478 | EGFR | ErbB | 1.33 | uM | 7811.044 | 0.9884 | 0.9254 | 0.3073 | |
| HCC1187 | TNBC | Basal A | AG1478 | EGFR | ErbB | 6.67 | uM | 7811.044 | 0.9951 | 0.9681 | 0.3073 | |
| HCC1187 | TNBC | Basal A | AG1478 | EGFR | ErbB | 33.3 | uM | 7811.044 | 1.0050 | 1.0325 | 0.3073 | |
| HCC1187 | TNBC | Basal A | AG1478 | EGFR | ErbB | 167 | uM | 7811.044 | 0.9971 | 0.9811 | 0.3073 | |
| HCC1187 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.000427 | uM | 7812.016 | 1.0082 | 1.0154 | 1.0628 | |
| HCC1187 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.00213 | uM | 7812.016 | 1.0190 | 1.0357 | 1.0628 | |
| HCC1187 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0107 | uM | 7812.016 | 1.0110 | 1.0208 | 1.0628 | |
| HCC1187 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0533 | uM | 7812.016 | 0.9033 | 0.8176 | 1.0628 | |
| HCC1187 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.267 | uM | 7812.016 | 0.9111 | 0.8323 | 1.0628 | |
| HCC1187 | TNBC | Basal A | AG1478 | EGFR | ErbB | 1.33 | uM | 7812.016 | 0.8936 | 0.7991 | 1.0628 | |
| HCC1187 | TNBC | Basal A | AG1478 | EGFR | ErbB | 6.67 | uM | 7812.016 | 0.8523 | 0.7209 | 1.0628 | |
| HCC1187 | TNBC | Basal A | AG1478 | EGFR | ErbB | 33.3 | uM | 7812.016 | 0.9423 | 0.8912 | 1.0628 | |
| HCC1187 | TNBC | Basal A | AG1478 | EGFR | ErbB | 167 | uM | 7812.016 | 0.8482 | 0.7129 | 1.0628 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.000427 | uM | 7813.016 | 1.0543 | 1.1278 | 0.8531 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.00213 | uM | 7813.016 | 1.0228 | 1.0535 | 0.8531 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0107 | uM | 7813.016 | 0.9069 | 0.7835 | 0.8531 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0533 | uM | 7813.016 | 1.0871 | 1.2056 | 0.8531 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.267 | uM | 7813.016 | 1.0911 | 1.2152 | 0.8531 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 1.33 | uM | 7813.016 | 1.0938 | 1.2216 | 0.8531 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 6.67 | uM | 7813.016 | 0.9089 | 0.7882 | 0.8531 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 33.3 | uM | 7813.016 | 1.0904 | 1.2136 | 0.8531 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 167 | uM | 7813.016 | 0.9458 | 0.8734 | 0.8531 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.000427 | uM | 7814.016 | 0.9863 | 0.9683 | 0.8623 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.00213 | uM | 7814.016 | 0.9503 | 0.8852 | 0.8623 |