Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HBL-100 | Unknown | Unknown | AG1478 | EGFR | ErbB | 6.67 | uM | 7808.016 | 0.9899 | 0.9910 | 2.2401 | |
| HBL-100 | Unknown | Unknown | AG1478 | EGFR | ErbB | 33.3 | uM | 7808.016 | 1.0089 | 1.0080 | 2.2401 | |
| HBL-100 | Unknown | Unknown | AG1478 | EGFR | ErbB | 167 | uM | 7808.016 | 0.9465 | 0.9515 | 2.2401 | |
| HCC1143 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.000427 | uM | 7809.016 | 1.0239 | 1.0286 | 1.6622 | |
| HCC1143 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.00213 | uM | 7809.016 | 0.9350 | 0.9207 | 1.6622 | |
| HCC1143 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0107 | uM | 7809.016 | 0.9780 | 0.9734 | 1.6622 | |
| HCC1143 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0533 | uM | 7809.016 | 0.8198 | 0.7747 | 1.6622 | |
| HCC1143 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.267 | uM | 7809.016 | 0.8910 | 0.8658 | 1.6622 | |
| HCC1143 | TNBC | Basal A | AG1478 | EGFR | ErbB | 1.33 | uM | 7809.016 | 0.8110 | 0.7632 | 1.6622 | |
| HCC1143 | TNBC | Basal A | AG1478 | EGFR | ErbB | 6.67 | uM | 7809.016 | 0.9443 | 0.9322 | 1.6622 | |
| HCC1143 | TNBC | Basal A | AG1478 | EGFR | ErbB | 33.3 | uM | 7809.016 | 0.8435 | 0.8053 | 1.6622 | |
| HCC1143 | TNBC | Basal A | AG1478 | EGFR | ErbB | 167 | uM | 7809.016 | 0.3916 | 0.1379 | 1.6622 | |
| HCC1143 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.000427 | uM | 7810.016 | 1.0639 | 1.1420 | 0.9032 | |
| HCC1143 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.00213 | uM | 7810.016 | 1.0313 | 1.0694 | 0.9032 | |
| HCC1143 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0107 | uM | 7810.016 | 0.9837 | 0.9639 | 0.9032 | |
| HCC1143 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0533 | uM | 7810.016 | 1.0360 | 1.0798 | 0.9032 | |
| HCC1143 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.267 | uM | 7810.016 | 1.0944 | 1.2101 | 0.9032 | |
| HCC1143 | TNBC | Basal A | AG1478 | EGFR | ErbB | 1.33 | uM | 7810.016 | 0.9921 | 0.9824 | 0.9032 | |
| HCC1143 | TNBC | Basal A | AG1478 | EGFR | ErbB | 6.67 | uM | 7810.016 | 0.9822 | 0.9606 | 0.9032 | |
| HCC1143 | TNBC | Basal A | AG1478 | EGFR | ErbB | 33.3 | uM | 7810.016 | 1.0081 | 1.0179 | 0.9032 | |
| HCC1143 | TNBC | Basal A | AG1478 | EGFR | ErbB | 167 | uM | 7810.016 | 0.9308 | 0.8473 | 0.9032 | |
| HCC1187 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.000427 | uM | 7811.044 | 0.9808 | 0.8779 | 0.3073 | |
| HCC1187 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.00213 | uM | 7811.044 | 0.9902 | 0.9369 | 0.3073 | |
| HCC1187 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0107 | uM | 7811.044 | 1.0155 | 1.1029 | 0.3073 | |
| HCC1187 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0533 | uM | 7811.044 | 0.9969 | 0.9802 | 0.3073 |