Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC202 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7841.016 | 0.6771 | -0.1604 | 0.4493 | |
| HCC202 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7841.016 | 0.2610 | -0.8994 | 0.4493 | |
| HCC202 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7841.016 | 0.3548 | -0.8007 | 0.4493 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 7845.016 | 0.9111 | 0.6179 | 0.4392 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 7845.016 | 1.0000 | 1.0000 | 0.4392 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 7845.016 | 0.9963 | 0.9831 | 0.4392 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 7845.016 | 0.9152 | 0.6344 | 0.4392 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7845.016 | 0.9166 | 0.6404 | 0.4392 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7845.016 | 0.9006 | 0.5756 | 0.4392 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7845.016 | 0.9163 | 0.6392 | 0.4392 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7845.016 | 0.7992 | 0.2007 | 0.4392 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7845.016 | 0.5282 | -0.5324 | 0.4392 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 7846.016 | 1.0358 | 1.2266 | 0.3279 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 7846.016 | 0.9954 | 0.9719 | 0.3279 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 7846.016 | 0.9506 | 0.7134 | 0.3279 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 7846.016 | 0.9552 | 0.7391 | 0.3279 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7846.016 | 0.9988 | 0.9926 | 0.3279 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7846.016 | 0.8919 | 0.4110 | 0.3279 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7846.016 | 0.9577 | 0.7530 | 0.3279 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7846.016 | 0.6064 | -0.5650 | 0.3279 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7846.016 | 0.6896 | -0.3562 | 0.3279 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 7848.016 | 1.0063 | 1.0264 | 0.4818 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 7848.016 | 0.9757 | 0.9004 | 0.4818 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 7848.016 | 1.0398 | 1.1686 | 0.4818 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 7848.016 | 0.9876 | 0.9487 | 0.4818 |