Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 167 | uM | 9024.016 | 0.5291 | 0.6435 | 3.2430 | |
| CAMA-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 7805.016 | 1.0390 | 1.0645 | 1.2059 | |
| CAMA-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 7805.016 | 1.0238 | 1.0394 | 1.2059 | |
| CAMA-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 7805.016 | 1.0410 | 1.0677 | 1.2059 | |
| CAMA-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 7805.016 | 0.9684 | 0.9475 | 1.2059 | |
| CAMA-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7805.016 | 1.0139 | 1.0230 | 1.2059 | |
| CAMA-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7805.016 | 1.0239 | 1.0395 | 1.2059 | |
| CAMA-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7805.016 | 1.0124 | 1.0206 | 1.2059 | |
| CAMA-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7805.016 | 0.7443 | 0.5656 | 1.2059 | |
| CAMA-1 | HR+ | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7805.016 | 0.1318 | -0.6274 | 1.2059 | |
| HBL-100 | Unknown | Unknown | AG1478 | EGFR | ErbB | 0.000427 | uM | 7807.016 | 0.9749 | 0.9765 | 2.1516 | |
| HBL-100 | Unknown | Unknown | AG1478 | EGFR | ErbB | 0.00213 | uM | 7807.016 | 0.9533 | 0.9560 | 2.1516 | |
| HBL-100 | Unknown | Unknown | AG1478 | EGFR | ErbB | 0.0107 | uM | 7807.016 | 0.9577 | 0.9602 | 2.1516 | |
| HBL-100 | Unknown | Unknown | AG1478 | EGFR | ErbB | 0.0533 | uM | 7807.016 | 0.9656 | 0.9677 | 2.1516 | |
| HBL-100 | Unknown | Unknown | AG1478 | EGFR | ErbB | 0.267 | uM | 7807.016 | 0.9057 | 0.9100 | 2.1516 | |
| HBL-100 | Unknown | Unknown | AG1478 | EGFR | ErbB | 1.33 | uM | 7807.016 | 0.9243 | 0.9282 | 2.1516 | |
| HBL-100 | Unknown | Unknown | AG1478 | EGFR | ErbB | 6.67 | uM | 7807.016 | 0.9446 | 0.9477 | 2.1516 | |
| HBL-100 | Unknown | Unknown | AG1478 | EGFR | ErbB | 33.3 | uM | 7807.016 | 0.9323 | 0.9359 | 2.1516 | |
| HBL-100 | Unknown | Unknown | AG1478 | EGFR | ErbB | 167 | uM | 7807.016 | 0.9439 | 0.9470 | 2.1516 | |
| HBL-100 | Unknown | Unknown | AG1478 | EGFR | ErbB | 0.000427 | uM | 7808.016 | 1.0414 | 1.0365 | 2.2401 | |
| HBL-100 | Unknown | Unknown | AG1478 | EGFR | ErbB | 0.00213 | uM | 7808.016 | 0.9886 | 0.9898 | 2.2401 | |
| HBL-100 | Unknown | Unknown | AG1478 | EGFR | ErbB | 0.0107 | uM | 7808.016 | 1.0391 | 1.0346 | 2.2401 | |
| HBL-100 | Unknown | Unknown | AG1478 | EGFR | ErbB | 0.0533 | uM | 7808.016 | 1.0798 | 1.0697 | 2.2401 | |
| HBL-100 | Unknown | Unknown | AG1478 | EGFR | ErbB | 0.267 | uM | 7808.016 | 1.1100 | 1.0954 | 2.2401 | |
| HBL-100 | Unknown | Unknown | AG1478 | EGFR | ErbB | 1.33 | uM | 7808.016 | 1.0194 | 1.0172 | 2.2401 |