Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 7485.093 | 0.9813 | 0.9895 | 3.5766 | |
| MCF 10A | NM | Basal B | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 7485.093 | 0.9898 | 0.9943 | 3.5766 | |
| MCF 10A | NM | Basal B | PD173074 | FGFR1/3 | RTK | 0.0107 | uM | 7485.093 | 0.9772 | 0.9871 | 3.5766 | |
| MCF 10A | NM | Basal B | PD173074 | FGFR1/3 | RTK | 0.0533 | uM | 7485.093 | 0.9562 | 0.9751 | 3.5766 | |
| MCF 10A | NM | Basal B | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 7485.093 | 0.9516 | 0.9724 | 3.5766 | |
| MCF 10A | NM | Basal B | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 7485.093 | 0.9120 | 0.9492 | 3.5766 | |
| MCF 10A | NM | Basal B | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 7485.093 | 0.7192 | 0.8240 | 3.5766 | |
| MCF 10A | NM | Basal B | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 7485.093 | 0.0532 | -0.1192 | 3.5766 | |
| MCF 10F | NM | - | PD173074 | FGFR1/3 | RTK | 0.000171 | uM | 7486.1 | 1.0147 | 1.0287 | 1.0281 | |
| MCF 10F | NM | - | PD173074 | FGFR1/3 | RTK | 0.000853 | uM | 7486.1 | 0.9851 | 0.9710 | 1.0281 | |
| MCF 10F | NM | - | PD173074 | FGFR1/3 | RTK | 0.00427 | uM | 7486.1 | 1.0615 | 1.1195 | 1.0281 | |
| MCF 10F | NM | - | PD173074 | FGFR1/3 | RTK | 0.0213 | uM | 7486.1 | 1.0869 | 1.1688 | 1.0281 | |
| MCF 10F | NM | - | PD173074 | FGFR1/3 | RTK | 0.107 | uM | 7486.1 | 0.9888 | 0.9783 | 1.0281 | |
| MCF 10F | NM | - | PD173074 | FGFR1/3 | RTK | 0.533 | uM | 7486.1 | 1.0263 | 1.0511 | 1.0281 | |
| MCF 10F | NM | - | PD173074 | FGFR1/3 | RTK | 2.67 | uM | 7486.1 | 0.9934 | 0.9872 | 1.0281 | |
| MCF 10F | NM | - | PD173074 | FGFR1/3 | RTK | 13.3 | uM | 7486.1 | 0.4499 | -0.0804 | 1.0281 | |
| MCF 10F | NM | - | PD173074 | FGFR1/3 | RTK | 66.7 | uM | 7486.1 | 0.1731 | -0.6368 | 1.0281 | |
| MCF12A | NM | Basal B | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 7490.093 | 1.0382 | 1.0319 | 2.3707 | |
| MCF12A | NM | Basal B | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 7490.093 | 0.9699 | 0.9744 | 2.3707 | |
| MCF12A | NM | Basal B | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 7490.093 | 0.9793 | 0.9825 | 2.3707 | |
| MCF12A | NM | Basal B | PD173074 | FGFR1/3 | RTK | 0.0107 | uM | 7490.093 | 0.9213 | 0.9320 | 2.3707 | |
| MCF12A | NM | Basal B | PD173074 | FGFR1/3 | RTK | 0.0533 | uM | 7490.093 | 0.9978 | 0.9981 | 2.3707 | |
| MCF12A | NM | Basal B | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 7490.093 | 0.9642 | 0.9695 | 2.3707 | |
| MCF12A | NM | Basal B | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 7490.093 | 0.9659 | 0.9710 | 2.3707 | |
| MCF12A | NM | Basal B | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 7490.093 | 0.9418 | 0.9501 | 2.3707 |