Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF12A | NM | Basal B | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 7490.093 | 0.2914 | 0.1889 | 2.3707 | |
| MDA-MB-134-VI | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 10419.093 | 1.0214 | 1.0753 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 10419.093 | 1.0171 | 1.0601 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 10419.093 | 1.0607 | 1.2172 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.0107 | uM | 10419.093 | 1.0049 | 1.0170 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.0533 | uM | 10419.093 | 0.9846 | 0.9464 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 10419.093 | 1.0093 | 1.0326 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 10419.093 | 0.9850 | 0.9479 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 10419.093 | 0.9589 | 0.8584 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 10419.093 | 0.7025 | 0.0787 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.000171 | uM | 10519.1 | 1.0334 | 1.0663 | 1.0071 | |
| MDA-MB-134-VI | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.000853 | uM | 10519.1 | 0.9919 | 0.9839 | 1.0071 | |
| MDA-MB-134-VI | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.00427 | uM | 10519.1 | 0.9819 | 0.9640 | 1.0071 | |
| MDA-MB-134-VI | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.0213 | uM | 10519.1 | 0.9817 | 0.9637 | 1.0071 | |
| MDA-MB-134-VI | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.107 | uM | 10519.1 | 0.9875 | 0.9752 | 1.0071 | |
| MDA-MB-134-VI | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.533 | uM | 10519.1 | 0.9696 | 0.9396 | 1.0071 | |
| MDA-MB-134-VI | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 2.67 | uM | 10519.1 | 1.0453 | 1.0899 | 1.0071 | |
| MDA-MB-134-VI | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 13.3 | uM | 10519.1 | 0.9627 | 0.9260 | 1.0071 | |
| MDA-MB-134-VI | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 66.7 | uM | 10519.1 | 0.0509 | -0.8961 | 1.0071 | |
| MDA-MB-157 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 7496.093 | 1.0247 | 1.0505 | 0.9777 | |
| MDA-MB-157 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 7496.093 | 0.9688 | 0.9361 | 0.9777 | |
| MDA-MB-157 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 7496.093 | 0.9798 | 0.9587 | 0.9777 | |
| MDA-MB-157 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.0107 | uM | 7496.093 | 0.9676 | 0.9338 | 0.9777 | |
| MDA-MB-157 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.0533 | uM | 7496.093 | 1.0051 | 1.0105 | 0.9777 | |
| MDA-MB-157 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 7496.093 | 0.8825 | 0.7599 | 0.9777 |