Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.000853 | uM | 10473.1 | 0.8624 | 0.7945 | 1.3652 | |
| CAMA-1 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.00427 | uM | 10473.1 | 0.9035 | 0.8567 | 1.3652 | |
| CAMA-1 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.0213 | uM | 10473.1 | 0.9590 | 0.9396 | 1.3652 | |
| CAMA-1 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.107 | uM | 10473.1 | 0.8645 | 0.7977 | 1.3652 | |
| CAMA-1 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.533 | uM | 10473.1 | 0.8501 | 0.7757 | 1.3652 | |
| CAMA-1 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 2.67 | uM | 10473.1 | 0.8964 | 0.8460 | 1.3652 | |
| CAMA-1 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 13.3 | uM | 10473.1 | 0.7672 | 0.6471 | 1.3652 | |
| CAMA-1 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 66.7 | uM | 10473.1 | 0.0161 | -0.9029 | 1.3652 | |
| HCC1143 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 7430.093 | 0.9975 | 0.9974 | 1.9432 | |
| HCC1143 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 7430.093 | 1.0310 | 1.0316 | 1.9432 | |
| HCC1143 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 7430.093 | 0.9989 | 0.9989 | 1.9432 | |
| HCC1143 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.0107 | uM | 7430.093 | 1.0067 | 1.0069 | 1.9432 | |
| HCC1143 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.0533 | uM | 7430.093 | 0.9823 | 0.9817 | 1.9432 | |
| HCC1143 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 7430.093 | 1.0680 | 1.0688 | 1.9432 | |
| HCC1143 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 7430.093 | 0.9787 | 0.9780 | 1.9432 | |
| HCC1143 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 7430.093 | 0.8221 | 0.8082 | 1.9432 | |
| HCC1143 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 7430.093 | 0.2455 | -0.0291 | 1.9432 | |
| HCC1187 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.000171 | uM | 7431.1 | 1.1153 | 1.1450 | 1.5594 | |
| HCC1187 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.000853 | uM | 7431.1 | 0.9870 | 0.9833 | 1.5594 | |
| HCC1187 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.00427 | uM | 7431.1 | 0.9974 | 0.9966 | 1.5594 | |
| HCC1187 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.0213 | uM | 7431.1 | 0.9958 | 0.9946 | 1.5594 | |
| HCC1187 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.107 | uM | 7431.1 | 0.9649 | 0.9547 | 1.5594 | |
| HCC1187 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.533 | uM | 7431.1 | 0.9753 | 0.9682 | 1.5594 | |
| HCC1187 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 2.67 | uM | 7431.1 | 0.9652 | 0.9550 | 1.5594 | |
| HCC1187 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 13.3 | uM | 7431.1 | 0.5630 | 0.3837 | 1.5594 |