Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 2920 | uM | 7543.095 | 0.9729 | 0.9542 | 1.1854 | |
| T47DKBLUC | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.00749 | uM | 7544.095 | 0.9068 | 0.8166 | 1.0175 | |
| T47DKBLUC | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.0374 | uM | 7544.095 | 0.9122 | 0.8273 | 1.0175 | |
| T47DKBLUC | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.187 | uM | 7544.095 | 0.9401 | 0.8821 | 1.0175 | |
| T47DKBLUC | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.936 | uM | 7544.095 | 0.8781 | 0.7602 | 1.0175 | |
| T47DKBLUC | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 4.68 | uM | 7544.095 | 0.8960 | 0.7954 | 1.0175 | |
| T47DKBLUC | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 23.4 | uM | 7544.095 | 0.8319 | 0.6690 | 1.0175 | |
| T47DKBLUC | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 117 | uM | 7544.095 | 0.8598 | 0.7240 | 1.0175 | |
| T47DKBLUC | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 585 | uM | 7544.095 | 0.8582 | 0.7209 | 1.0175 | |
| T47DKBLUC | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 2920 | uM | 7544.095 | 0.8519 | 0.7085 | 1.0175 | |
| T47DKBLUC | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.00749 | uM | 7545.095 | 0.9338 | 0.8692 | 1.0123 | |
| T47DKBLUC | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.0374 | uM | 7545.095 | 0.9392 | 0.8797 | 1.0123 | |
| T47DKBLUC | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.187 | uM | 7545.095 | 0.9225 | 0.8467 | 1.0123 | |
| T47DKBLUC | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.936 | uM | 7545.095 | 0.8841 | 0.7709 | 1.0123 | |
| T47DKBLUC | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 4.68 | uM | 7545.095 | 0.8698 | 0.7425 | 1.0123 | |
| T47DKBLUC | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 23.4 | uM | 7545.095 | 0.8307 | 0.6651 | 1.0123 | |
| T47DKBLUC | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 117 | uM | 7545.095 | 0.8324 | 0.6684 | 1.0123 | |
| T47DKBLUC | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 585 | uM | 7545.095 | 0.8559 | 0.7150 | 1.0123 | |
| T47DKBLUC | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 2920 | uM | 7545.095 | 0.8827 | 0.7681 | 1.0123 | |
| T47DKBLUC | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.00749 | uM | 7546.095 | 0.9991 | 0.9977 | 0.8399 | |
| T47DKBLUC | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.0374 | uM | 7546.095 | 0.9975 | 0.9940 | 0.8399 | |
| T47DKBLUC | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.187 | uM | 7546.095 | 0.8146 | 0.5667 | 0.8399 | |
| T47DKBLUC | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.936 | uM | 7546.095 | 0.7507 | 0.4215 | 0.8399 | |
| T47DKBLUC | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 4.68 | uM | 7546.095 | 0.7022 | 0.3129 | 0.8399 | |
| T47DKBLUC | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 23.4 | uM | 7546.095 | 0.7188 | 0.3499 | 0.8399 |