Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
MDA-MB-361
HER2amp
Luminal
PD 98059
MEK
MAPK
0.000128
uM
12379.152
0.9716 0.8940 0.5297
MDA-MB-361
HER2amp
Luminal
PD 98059
MEK
MAPK
0.00064
uM
12379.152
1.0387 1.1486 0.5297
MDA-MB-361
HER2amp
Luminal
PD 98059
MEK
MAPK
0.0032
uM
12379.152
0.9278 0.7363 0.5297
MDA-MB-361
HER2amp
Luminal
PD 98059
MEK
MAPK
0.016
uM
12379.152
1.0029 1.0110 0.5297
MDA-MB-361
HER2amp
Luminal
PD 98059
MEK
MAPK
0.08
uM
12379.152
1.0446 1.1716 0.5297
MDA-MB-361
HER2amp
Luminal
PD 98059
MEK
MAPK
0.4
uM
12379.152
1.0299 1.1144 0.5297
MDA-MB-361
HER2amp
Luminal
PD 98059
MEK
MAPK
2
uM
12379.152
1.0021 1.0078 0.5297
MDA-MB-361
HER2amp
Luminal
PD 98059
MEK
MAPK
10
uM
12379.152
0.9619 0.8587 0.5297
MDA-MB-361
HER2amp
Luminal
PD 98059
MEK
MAPK
50
uM
12379.152
0.9020 0.6460 0.5297
MDA-MB-415
HR+
Luminal
PD 98059
MEK
MAPK
0.000128
uM
10938.152
0.6373 0.2447 0.9498
MDA-MB-415
HR+
Luminal
PD 98059
MEK
MAPK
0.00064
uM
10938.152
0.8430 0.6709 0.9498
MDA-MB-415
HR+
Luminal
PD 98059
MEK
MAPK
0.0032
uM
10938.152
0.6815 0.3356 0.9498
MDA-MB-415
HR+
Luminal
PD 98059
MEK
MAPK
0.016
uM
10938.152
0.9897 0.9783 0.9498
MDA-MB-415
HR+
Luminal
PD 98059
MEK
MAPK
0.08
uM
10938.152
0.4206 -0.1965 0.9498
MDA-MB-415
HR+
Luminal
PD 98059
MEK
MAPK
0.4
uM
10938.152
0.8481 0.6815 0.9498
MDA-MB-415
HR+
Luminal
PD 98059
MEK
MAPK
2
uM
10938.152
0.9212 0.8345 0.9498
MDA-MB-415
HR+
Luminal
PD 98059
MEK
MAPK
10
uM
10938.152
0.9233 0.8388 0.9498
MDA-MB-415
HR+
Luminal
PD 98059
MEK
MAPK
50
uM
10938.152
0.8253 0.6339 0.9498
MDA-MB-415
HR+
Luminal
PD 98059
MEK
MAPK
0.000128
uM
12333.152
0.9160 0.7754 0.7371
MDA-MB-415
HR+
Luminal
PD 98059
MEK
MAPK
0.00064
uM
12333.152
0.9256 0.8008 0.7371
MDA-MB-415
HR+
Luminal
PD 98059
MEK
MAPK
0.0032
uM
12333.152
1.0108 1.0293 0.7371
MDA-MB-415
HR+
Luminal
PD 98059
MEK
MAPK
0.016
uM
12333.152
0.9149 0.7727 0.7371
MDA-MB-415
HR+
Luminal
PD 98059
MEK
MAPK
0.08
uM
12333.152
0.9959 0.9889 0.7371
MDA-MB-415
HR+
Luminal
PD 98059
MEK
MAPK
0.4
uM
12333.152
0.9174 0.7792 0.7371
MDA-MB-415
HR+
Luminal
PD 98059
MEK
MAPK
2
uM
12333.152
0.9503 0.8663 0.7371