Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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MDA-MB-361 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 0.000128 | uM | 12379.152 | 0.9716 | 0.8940 | 0.5297 | |
MDA-MB-361 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 0.00064 | uM | 12379.152 | 1.0387 | 1.1486 | 0.5297 | |
MDA-MB-361 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 0.0032 | uM | 12379.152 | 0.9278 | 0.7363 | 0.5297 | |
MDA-MB-361 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 0.016 | uM | 12379.152 | 1.0029 | 1.0110 | 0.5297 | |
MDA-MB-361 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 0.08 | uM | 12379.152 | 1.0446 | 1.1716 | 0.5297 | |
MDA-MB-361 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 0.4 | uM | 12379.152 | 1.0299 | 1.1144 | 0.5297 | |
MDA-MB-361 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 2 | uM | 12379.152 | 1.0021 | 1.0078 | 0.5297 | |
MDA-MB-361 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 10 | uM | 12379.152 | 0.9619 | 0.8587 | 0.5297 | |
MDA-MB-361 | HER2amp | Luminal | PD 98059 | MEK | MAPK | 50 | uM | 12379.152 | 0.9020 | 0.6460 | 0.5297 | |
MDA-MB-415 | HR+ | Luminal | PD 98059 | MEK | MAPK | 0.000128 | uM | 10938.152 | 0.6373 | 0.2447 | 0.9498 | |
MDA-MB-415 | HR+ | Luminal | PD 98059 | MEK | MAPK | 0.00064 | uM | 10938.152 | 0.8430 | 0.6709 | 0.9498 | |
MDA-MB-415 | HR+ | Luminal | PD 98059 | MEK | MAPK | 0.0032 | uM | 10938.152 | 0.6815 | 0.3356 | 0.9498 | |
MDA-MB-415 | HR+ | Luminal | PD 98059 | MEK | MAPK | 0.016 | uM | 10938.152 | 0.9897 | 0.9783 | 0.9498 | |
MDA-MB-415 | HR+ | Luminal | PD 98059 | MEK | MAPK | 0.08 | uM | 10938.152 | 0.4206 | -0.1965 | 0.9498 | |
MDA-MB-415 | HR+ | Luminal | PD 98059 | MEK | MAPK | 0.4 | uM | 10938.152 | 0.8481 | 0.6815 | 0.9498 | |
MDA-MB-415 | HR+ | Luminal | PD 98059 | MEK | MAPK | 2 | uM | 10938.152 | 0.9212 | 0.8345 | 0.9498 | |
MDA-MB-415 | HR+ | Luminal | PD 98059 | MEK | MAPK | 10 | uM | 10938.152 | 0.9233 | 0.8388 | 0.9498 | |
MDA-MB-415 | HR+ | Luminal | PD 98059 | MEK | MAPK | 50 | uM | 10938.152 | 0.8253 | 0.6339 | 0.9498 | |
MDA-MB-415 | HR+ | Luminal | PD 98059 | MEK | MAPK | 0.000128 | uM | 12333.152 | 0.9160 | 0.7754 | 0.7371 | |
MDA-MB-415 | HR+ | Luminal | PD 98059 | MEK | MAPK | 0.00064 | uM | 12333.152 | 0.9256 | 0.8008 | 0.7371 | |
MDA-MB-415 | HR+ | Luminal | PD 98059 | MEK | MAPK | 0.0032 | uM | 12333.152 | 1.0108 | 1.0293 | 0.7371 | |
MDA-MB-415 | HR+ | Luminal | PD 98059 | MEK | MAPK | 0.016 | uM | 12333.152 | 0.9149 | 0.7727 | 0.7371 | |
MDA-MB-415 | HR+ | Luminal | PD 98059 | MEK | MAPK | 0.08 | uM | 12333.152 | 0.9959 | 0.9889 | 0.7371 | |
MDA-MB-415 | HR+ | Luminal | PD 98059 | MEK | MAPK | 0.4 | uM | 12333.152 | 0.9174 | 0.7792 | 0.7371 | |
MDA-MB-415 | HR+ | Luminal | PD 98059 | MEK | MAPK | 2 | uM | 12333.152 | 0.9503 | 0.8663 | 0.7371 |