Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-175-VII	HR+	Luminal	PD 98059	MEK	MAPK	0.0064	uM	12126.159	0.9352	0.8267	0.7389
MDA-MB-175-VII	HR+	Luminal	PD 98059	MEK	MAPK	0.032	uM	12126.159	0.8691	0.6541	0.7389
MDA-MB-175-VII	HR+	Luminal	PD 98059	MEK	MAPK	0.16	uM	12126.159	0.9192	0.7845	0.7389
MDA-MB-175-VII	HR+	Luminal	PD 98059	MEK	MAPK	0.8	uM	12126.159	0.9092	0.7581	0.7389
MDA-MB-175-VII	HR+	Luminal	PD 98059	MEK	MAPK	4	uM	12126.159	0.8801	0.6825	0.7389
MDA-MB-175-VII	HR+	Luminal	PD 98059	MEK	MAPK	20	uM	12126.159	0.8459	0.5946	0.7389
MDA-MB-175-VII	HR+	Luminal	PD 98059	MEK	MAPK	100	uM	12126.159	0.7026	0.2403	0.7389
MDA-MB-361	HER2amp	Luminal	PD 98059	MEK	MAPK	0.000256	uM	10643.136	1.0362	1.1432	0.5141
MDA-MB-361	HER2amp	Luminal	PD 98059	MEK	MAPK	0.00128	uM	10643.136	1.0559	1.2231	0.5141
MDA-MB-361	HER2amp	Luminal	PD 98059	MEK	MAPK	0.0064	uM	10643.136	1.0262	1.1031	0.5141
MDA-MB-361	HER2amp	Luminal	PD 98059	MEK	MAPK	0.032	uM	10643.136	1.0204	1.0802	0.5141
MDA-MB-361	HER2amp	Luminal	PD 98059	MEK	MAPK	0.16	uM	10643.136	0.9857	0.9447	0.5141
MDA-MB-361	HER2amp	Luminal	PD 98059	MEK	MAPK	0.8	uM	10643.136	0.9846	0.9405	0.5141
MDA-MB-361	HER2amp	Luminal	PD 98059	MEK	MAPK	4	uM	10643.136	0.9756	0.9060	0.5141
MDA-MB-361	HER2amp	Luminal	PD 98059	MEK	MAPK	20	uM	10643.136	0.9132	0.6761	0.5141
MDA-MB-361	HER2amp	Luminal	PD 98059	MEK	MAPK	100	uM	10643.136	0.7912	0.2680	0.5141
MDA-MB-361	HER2amp	Luminal	PD 98059	MEK	MAPK	0.000128	uM	10999.152	0.9704	0.9299	0.8426
MDA-MB-361	HER2amp	Luminal	PD 98059	MEK	MAPK	0.00064	uM	10999.152	0.9397	0.8578	0.8426
MDA-MB-361	HER2amp	Luminal	PD 98059	MEK	MAPK	0.0032	uM	10999.152	0.9828	0.9591	0.8426
MDA-MB-361	HER2amp	Luminal	PD 98059	MEK	MAPK	0.016	uM	10999.152	0.9672	0.9225	0.8426
MDA-MB-361	HER2amp	Luminal	PD 98059	MEK	MAPK	0.08	uM	10999.152	1.0233	1.0555	0.8426
MDA-MB-361	HER2amp	Luminal	PD 98059	MEK	MAPK	0.4	uM	10999.152	0.9852	0.9649	0.8426
MDA-MB-361	HER2amp	Luminal	PD 98059	MEK	MAPK	2	uM	10999.152	1.0087	1.0206	0.8426
MDA-MB-361	HER2amp	Luminal	PD 98059	MEK	MAPK	10	uM	10999.152	0.9439	0.8674	0.8426
MDA-MB-361	HER2amp	Luminal	PD 98059	MEK	MAPK	50	uM	10999.152	0.9140	0.7974	0.8426

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)