Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
MDA-MB-157
TNBC
Basal B
 PD 98059
MEK
MAPK
0.08
uM
12594.152
 1.0673 1.1021 1.3085
MDA-MB-157
TNBC
Basal B
 PD 98059
MEK
MAPK
0.4
uM
12594.152
 1.0549 1.0834 1.3085
MDA-MB-157
TNBC
Basal B
 PD 98059
MEK
MAPK
2
uM
12594.152
 1.1017 1.1537 1.3085
MDA-MB-157
TNBC
Basal B
 PD 98059
MEK
MAPK
10
uM
12594.152
 1.0833 1.1261 1.3085
MDA-MB-157
TNBC
Basal B
 PD 98059
MEK
MAPK
50
uM
12594.152
 1.0089 1.0136 1.3085
MDA-MB-175-VII
HR+
Luminal
 PD 98059
MEK
MAPK
0.000256
uM
10642.136
 0.9493 0.8094 0.5193
MDA-MB-175-VII
HR+
Luminal
 PD 98059
MEK
MAPK
0.00128
uM
10642.136
 0.9566 0.8361 0.5193
MDA-MB-175-VII
HR+
Luminal
 PD 98059
MEK
MAPK
0.0064
uM
10642.136
 0.9935 0.9749 0.5193
MDA-MB-175-VII
HR+
Luminal
 PD 98059
MEK
MAPK
0.032
uM
10642.136
 0.9793 0.9212 0.5193
MDA-MB-175-VII
HR+
Luminal
 PD 98059
MEK
MAPK
0.16
uM
10642.136
 0.9555 0.8321 0.5193
MDA-MB-175-VII
HR+
Luminal
 PD 98059
MEK
MAPK
0.8
uM
10642.136
 0.9700 0.8860 0.5193
MDA-MB-175-VII
HR+
Luminal
 PD 98059
MEK
MAPK
4
uM
10642.136
 0.9427 0.7853 0.5193
MDA-MB-175-VII
HR+
Luminal
 PD 98059
MEK
MAPK
20
uM
10642.136
 0.8020 0.3078 0.5193
MDA-MB-175-VII
HR+
Luminal
 PD 98059
MEK
MAPK
100
uM
10642.136
 0.6635 -0.0923 0.5193
MDA-MB-175-VII
HR+
Luminal
 PD 98059
MEK
MAPK
0.000128
uM
10818.152
 0.9783 0.9055 0.4535
MDA-MB-175-VII
HR+
Luminal
 PD 98059
MEK
MAPK
0.00064
uM
10818.152
 0.9728 0.8819 0.4535
MDA-MB-175-VII
HR+
Luminal
 PD 98059
MEK
MAPK
0.0032
uM
10818.152
 0.9655 0.8510 0.4535
MDA-MB-175-VII
HR+
Luminal
 PD 98059
MEK
MAPK
0.016
uM
10818.152
 1.0277 1.1242 0.4535
MDA-MB-175-VII
HR+
Luminal
 PD 98059
MEK
MAPK
0.08
uM
10818.152
 0.9917 0.9634 0.4535
MDA-MB-175-VII
HR+
Luminal
 PD 98059
MEK
MAPK
0.4
uM
10818.152
 0.9754 0.8932 0.4535
MDA-MB-175-VII
HR+
Luminal
 PD 98059
MEK
MAPK
2
uM
10818.152
 0.9940 0.9736 0.4535
MDA-MB-175-VII
HR+
Luminal
 PD 98059
MEK
MAPK
10
uM
10818.152
 0.9654 0.8507 0.4535
MDA-MB-175-VII
HR+
Luminal
 PD 98059
MEK
MAPK
50
uM
10818.152
 0.7966 0.2113 0.4535
MDA-MB-175-VII
HR+
Luminal
 PD 98059
MEK
MAPK
0.000256
uM
12126.159
 0.8839 0.6924 0.7389
MDA-MB-175-VII
HR+
Luminal
 PD 98059
MEK
MAPK
0.00128
uM
12126.159
 0.9120 0.7655 0.7389