Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | Oxamflatin | HDAC | HDAC | 2.67 | uM | 12000.147 | 0.7263 | 0.3823 | 0.8658 | |
| HCC1395 | TNBC | Basal B | Oxamflatin | HDAC | HDAC | 13.3 | uM | 12000.147 | 0.1400 | -0.7936 | 0.8658 | |
| HCC1395 | TNBC | Basal B | Oxamflatin | HDAC | HDAC | 66.7 | uM | 12000.147 | 0.0159 | -0.9833 | 0.8658 | |
| HCC1395 | TNBC | Basal B | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 12084.147 | 1.0300 | 1.0551 | 1.0888 | |
| HCC1395 | TNBC | Basal B | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 12084.147 | 1.1134 | 1.2073 | 1.0888 | |
| HCC1395 | TNBC | Basal B | Oxamflatin | HDAC | HDAC | 0.00427 | uM | 12084.147 | 0.9800 | 0.9632 | 1.0888 | |
| HCC1395 | TNBC | Basal B | Oxamflatin | HDAC | HDAC | 0.0213 | uM | 12084.147 | 1.0180 | 1.0331 | 1.0888 | |
| HCC1395 | TNBC | Basal B | Oxamflatin | HDAC | HDAC | 0.107 | uM | 12084.147 | 1.0113 | 1.0208 | 1.0888 | |
| HCC1395 | TNBC | Basal B | Oxamflatin | HDAC | HDAC | 0.533 | uM | 12084.147 | 1.0127 | 1.0233 | 1.0888 | |
| HCC1395 | TNBC | Basal B | Oxamflatin | HDAC | HDAC | 2.67 | uM | 12084.147 | 0.6099 | 0.2699 | 1.0888 | |
| HCC1395 | TNBC | Basal B | Oxamflatin | HDAC | HDAC | 13.3 | uM | 12084.147 | 0.1604 | -0.6276 | 1.0888 | |
| HCC1395 | TNBC | Basal B | Oxamflatin | HDAC | HDAC | 66.7 | uM | 12084.147 | 0.0020 | -0.9934 | 1.0888 | |
| HCC1419 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 12001.147 | 0.8784 | 0.6108 | 0.5989 | |
| HCC1419 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 12001.147 | 0.9319 | 0.7779 | 0.5989 | |
| HCC1419 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.00427 | uM | 12001.147 | 0.9138 | 0.7206 | 0.5989 | |
| HCC1419 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.0213 | uM | 12001.147 | 0.9840 | 0.9469 | 0.5989 | |
| HCC1419 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.107 | uM | 12001.147 | 0.8865 | 0.6354 | 0.5989 | |
| HCC1419 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.533 | uM | 12001.147 | 0.9615 | 0.8732 | 0.5989 | |
| HCC1419 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 2.67 | uM | 12001.147 | 0.7066 | 0.1199 | 0.5989 | |
| HCC1419 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 13.3 | uM | 12001.147 | 0.3539 | -0.6470 | 0.5989 | |
| HCC1419 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 66.7 | uM | 12001.147 | 0.0112 | -0.9989 | 0.5989 | |
| HCC1428 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 10693.147 | 0.9950 | 0.9887 | 0.8879 | |
| HCC1428 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 10693.147 | 0.9764 | 0.9469 | 0.8879 | |
| HCC1428 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.00427 | uM | 10693.147 | 0.9895 | 0.9764 | 0.8879 | |
| HCC1428 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.0213 | uM | 10693.147 | 0.9710 | 0.9349 | 0.8879 |