Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.107 | uM | 10693.147 | 0.9910 | 0.9798 | 0.8879 | |
| HCC1428 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.533 | uM | 10693.147 | 0.7664 | 0.4822 | 0.8879 | |
| HCC1428 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 2.67 | uM | 10693.147 | 0.0400 | -0.9468 | 0.8879 | |
| HCC1428 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 13.3 | uM | 10693.147 | 0.0349 | -0.9544 | 0.8879 | |
| HCC1428 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 66.7 | uM | 10693.147 | 0.0432 | -0.9418 | 0.8879 | |
| HCC1428 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 11936.147 | 0.9274 | 0.8425 | 0.9187 | |
| HCC1428 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 11936.147 | 0.8668 | 0.7119 | 0.9187 | |
| HCC1428 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.00427 | uM | 11936.147 | 0.9426 | 0.8754 | 0.9187 | |
| HCC1428 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.0213 | uM | 11936.147 | 0.8903 | 0.7624 | 0.9187 | |
| HCC1428 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.107 | uM | 11936.147 | 0.9169 | 0.8198 | 0.9187 | |
| HCC1428 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.533 | uM | 11936.147 | 0.6652 | 0.2834 | 0.9187 | |
| HCC1428 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 2.67 | uM | 11936.147 | 0.0242 | -0.9652 | 0.9187 | |
| HCC1428 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 13.3 | uM | 11936.147 | 0.0199 | -0.9719 | 0.9187 | |
| HCC1428 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 66.7 | uM | 11936.147 | 0.0346 | -0.9485 | 0.9187 | |
| HCC1569 | HER2amp | Basal A | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 10872.147 | 0.9556 | 0.9449 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 10872.147 | 1.0203 | 1.0248 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | Oxamflatin | HDAC | HDAC | 0.00427 | uM | 10872.147 | 0.8801 | 0.8489 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | Oxamflatin | HDAC | HDAC | 0.0213 | uM | 10872.147 | 0.9769 | 0.9714 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | Oxamflatin | HDAC | HDAC | 0.107 | uM | 10872.147 | 0.9192 | 0.8990 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | Oxamflatin | HDAC | HDAC | 0.533 | uM | 10872.147 | 0.7097 | 0.6196 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | Oxamflatin | HDAC | HDAC | 2.67 | uM | 10872.147 | 0.3239 | -0.0004 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | Oxamflatin | HDAC | HDAC | 13.3 | uM | 10872.147 | 0.0351 | -0.7451 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | Oxamflatin | HDAC | HDAC | 66.7 | uM | 10872.147 | 0.0244 | -0.7963 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 12523.147 | 1.0053 | 1.0115 | 0.9214 | |
| HCC1569 | HER2amp | Basal A | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 12523.147 | 1.0175 | 1.0380 | 0.9214 |