Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7819.075 | 0.3987 | -0.6373 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7819.075 | 0.0842 | -0.9798 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7820.011 | 0.9977 | 0.9931 | 0.6709 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7820.011 | 0.9761 | 0.9291 | 0.6709 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7820.011 | 0.9931 | 0.9796 | 0.6709 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7820.011 | 0.9782 | 0.9352 | 0.6709 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7820.011 | 0.9495 | 0.8513 | 0.6709 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 7820.011 | 0.8625 | 0.6044 | 0.6709 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7820.011 | 0.9257 | 0.7825 | 0.6709 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7820.011 | 0.3017 | -0.6648 | 0.6709 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7820.011 | 0.1030 | -0.9325 | 0.6709 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9278.011 | 1.0410 | 1.1537 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9278.011 | 0.9580 | 0.8482 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9278.011 | 1.0898 | 1.3430 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9278.011 | 1.0060 | 1.0221 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9278.011 | 0.9593 | 0.8526 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9278.011 | 0.8278 | 0.4125 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9278.011 | 0.8051 | 0.3421 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9278.011 | 0.3787 | -0.6650 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9278.011 | 0.0898 | -0.9763 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 10019.12 | 0.9945 | 0.9775 | 0.4898 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 10019.12 | 0.9720 | 0.8874 | 0.4898 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 10019.12 | 1.0150 | 1.0616 | 0.4898 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 10019.12 | 0.9882 | 0.9522 | 0.4898 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 10019.12 | 1.0315 | 1.1308 | 0.4898 |