Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9254.12 | 0.9931 | 0.9876 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9254.12 | 0.9530 | 0.9154 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9254.12 | 1.0627 | 1.1121 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9254.12 | 0.8929 | 0.8066 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9254.12 | 0.9438 | 0.8988 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9254.12 | 0.8668 | 0.7591 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9254.12 | 0.5431 | 0.1561 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9254.12 | 0.0450 | -0.8764 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9254.12 | 0.0006 | -0.9973 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9258.011 | 0.9702 | 0.9152 | 0.6984 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9258.011 | 1.0545 | 1.1580 | 0.6984 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9258.011 | 1.0700 | 1.2034 | 0.6984 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9258.011 | 1.0563 | 1.1631 | 0.6984 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9258.011 | 0.9407 | 0.8324 | 0.6984 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9258.011 | 0.8945 | 0.7048 | 0.6984 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9258.011 | 0.5790 | -0.0855 | 0.6984 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9258.011 | 0.0610 | -0.9636 | 0.6984 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9258.011 | 0.0015 | -0.9998 | 0.6984 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7819.075 | 1.0149 | 1.0558 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00806 | uM | 7819.075 | 1.0195 | 1.0731 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7819.075 | 1.0621 | 1.2368 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7819.075 | 0.9629 | 0.8645 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7819.075 | 0.9885 | 0.9575 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.04 | uM | 7819.075 | 0.9006 | 0.6465 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7819.075 | 0.8638 | 0.5239 | 0.5386 |