Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 7466.093 | 0.9321 | 0.8420 | 0.8543 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 7466.093 | 0.5397 | -0.0284 | 0.8543 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.000171 | uM | 10577.1 | 1.0505 | 1.1155 | 0.8774 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.000853 | uM | 10577.1 | 0.9693 | 0.9301 | 0.8774 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.00427 | uM | 10577.1 | 0.9950 | 0.9885 | 0.8774 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.0213 | uM | 10577.1 | 1.0154 | 1.0350 | 0.8774 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.107 | uM | 10577.1 | 1.0552 | 1.1263 | 0.8774 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.533 | uM | 10577.1 | 1.0471 | 1.1078 | 0.8774 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 2.67 | uM | 10577.1 | 1.0688 | 1.1577 | 0.8774 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 13.3 | uM | 10577.1 | 0.9604 | 0.9100 | 0.8774 | |
| HCC3153 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 66.7 | uM | 10577.1 | 0.4090 | -0.2781 | 0.8774 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 7468.093 | 1.0141 | 1.0202 | 1.4007 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 7468.093 | 0.9688 | 0.9553 | 1.4007 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 7468.093 | 0.9985 | 0.9978 | 1.4007 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.0107 | uM | 7468.093 | 0.9755 | 0.9649 | 1.4007 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.0533 | uM | 7468.093 | 0.9529 | 0.9323 | 1.4007 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 7468.093 | 0.7753 | 0.6676 | 1.4007 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 7468.093 | 0.6972 | 0.5460 | 1.4007 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 7468.093 | 0.6623 | 0.4904 | 1.4007 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 7468.093 | 0.0458 | -0.7786 | 1.4007 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 10418.093 | 1.0299 | 1.0606 | 0.9872 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 10418.093 | 1.0059 | 1.0119 | 0.9872 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 10418.093 | 0.9615 | 0.9220 | 0.9872 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.0107 | uM | 10418.093 | 1.0272 | 1.0551 | 0.9872 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.0533 | uM | 10418.093 | 1.0085 | 1.0171 | 0.9872 |