Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9244.021 | 1.1256 | 1.5954 | 0.4542 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9244.021 | 1.0534 | 1.2425 | 0.4542 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9244.021 | 1.0179 | 1.0797 | 0.4542 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9244.021 | 0.3072 | -0.8512 | 0.4542 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9244.021 | 0.0312 | -0.9990 | 0.4542 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9244.021 | 0.0790 | -0.9925 | 0.4542 | |
| HCC1187 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9244.021 | 0.0192 | -0.9997 | 0.4542 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7813.011 | 1.0926 | 1.2137 | 0.8718 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7813.011 | 0.9610 | 0.9108 | 0.8718 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7813.011 | 1.0674 | 1.1555 | 0.8718 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7813.011 | 1.0807 | 1.1861 | 0.8718 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7813.011 | 1.1058 | 1.2445 | 0.8718 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 7813.011 | 0.9035 | 0.7802 | 0.8718 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7813.011 | 0.6198 | 0.1555 | 0.8718 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7813.011 | 0.0519 | -0.9328 | 0.8718 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7813.011 | 0.0020 | -0.9984 | 0.8718 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7814.011 | 1.0060 | 1.0126 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7814.011 | 0.9451 | 0.8842 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7814.011 | 1.0060 | 1.0126 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7814.011 | 0.9682 | 0.9330 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7814.011 | 0.9545 | 0.9041 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 7814.011 | 0.7426 | 0.4607 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7814.011 | 0.5297 | 0.0225 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7814.011 | 0.0379 | -0.9368 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7814.011 | 0.0090 | -0.9862 | 0.9472 |