Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 10418.093 | 0.9056 | 0.8089 | 0.9872 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 10418.093 | 0.8399 | 0.6761 | 0.9872 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 10418.093 | 0.6185 | 0.2294 | 0.9872 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 10418.093 | 0.0505 | -0.9028 | 0.9872 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.000171 | uM | 10578.1 | 1.0303 | 1.0372 | 1.6202 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.000853 | uM | 10578.1 | 0.9376 | 0.9220 | 1.6202 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.00427 | uM | 10578.1 | 0.9690 | 0.9615 | 1.6202 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.0213 | uM | 10578.1 | 0.8518 | 0.8114 | 1.6202 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.107 | uM | 10578.1 | 0.7575 | 0.6849 | 1.6202 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.533 | uM | 10578.1 | 0.7419 | 0.6634 | 1.6202 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 2.67 | uM | 10578.1 | 0.7564 | 0.6835 | 1.6202 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 13.3 | uM | 10578.1 | 0.4965 | 0.2982 | 1.6202 | |
| HCC38 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 66.7 | uM | 10578.1 | 0.0028 | -0.9474 | 1.6202 | |
| HCC70 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 7470.093 | 1.0060 | 1.0110 | 1.0798 | |
| HCC70 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 7470.093 | 0.9447 | 0.8974 | 1.0798 | |
| HCC70 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 7470.093 | 1.0108 | 1.0200 | 1.0798 | |
| HCC70 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.0107 | uM | 7470.093 | 0.9887 | 0.9791 | 1.0798 | |
| HCC70 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.0533 | uM | 7470.093 | 0.9782 | 0.9595 | 1.0798 | |
| HCC70 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 7470.093 | 0.9632 | 0.9318 | 1.0798 | |
| HCC70 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 7470.093 | 1.0402 | 1.0744 | 1.0798 | |
| HCC70 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 7470.093 | 0.7909 | 0.6094 | 1.0798 | |
| HCC70 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 7470.093 | 0.3641 | -0.2154 | 1.0798 | |
| Hs 578T | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.000171 | uM | 7472.1 | 1.4962 | 1.8735 | 1.1120 | |
| Hs 578T | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.000853 | uM | 7472.1 | 1.3845 | 1.6797 | 1.1120 | |
| Hs 578T | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 0.00427 | uM | 7472.1 | 1.0740 | 1.1326 | 1.1120 |