Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 10019.12 | 0.8540 | 0.4490 | 0.4898 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 10019.12 | 0.8025 | 0.2761 | 0.4898 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 10019.12 | 0.3047 | -0.8233 | 0.4898 | |
| HCC1419 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 10019.12 | 0.0412 | -0.9970 | 0.4898 | |
| HCC1428 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9294.011 | 1.0083 | 1.0230 | 0.7255 | |
| HCC1428 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9294.011 | 1.0123 | 1.0339 | 0.7255 | |
| HCC1428 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9294.011 | 1.0043 | 1.0119 | 0.7255 | |
| HCC1428 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9294.011 | 1.0066 | 1.0181 | 0.7255 | |
| HCC1428 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9294.011 | 0.9920 | 0.9781 | 0.7255 | |
| HCC1428 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9294.011 | 0.8911 | 0.7060 | 0.7255 | |
| HCC1428 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9294.011 | 0.1287 | -0.8815 | 0.7255 | |
| HCC1428 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9294.011 | 0.0295 | -0.9844 | 0.7255 | |
| HCC1428 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9294.011 | 0.0263 | -0.9867 | 0.7255 | |
| HCC1428 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 10031.021 | 1.0772 | 1.1840 | 0.8450 | |
| HCC1428 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 10031.021 | 1.0055 | 1.0131 | 0.8450 | |
| HCC1428 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 10031.021 | 1.0623 | 1.1482 | 0.8450 | |
| HCC1428 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 10031.021 | 0.9627 | 0.9121 | 0.8450 | |
| HCC1428 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 10031.021 | 1.0099 | 1.0235 | 0.8450 | |
| HCC1428 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 10031.021 | 0.9073 | 0.7826 | 0.8450 | |
| HCC1428 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 10031.021 | 0.1715 | -0.7518 | 0.8450 | |
| HCC1428 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 10031.021 | 0.0622 | -0.9252 | 0.8450 | |
| HCC1428 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 10031.021 | 0.0375 | -0.9589 | 0.8450 | |
| HCC1569 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7825.011 | 0.9599 | 0.9581 | 1.9334 | |
| HCC1569 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7825.011 | 1.0319 | 1.0327 | 1.9334 | |
| HCC1569 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7825.011 | 1.0323 | 1.0332 | 1.9334 |