Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7825.011 | 0.8067 | 0.7897 | 1.9334 | |
| HCC1569 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7825.011 | 0.6785 | 0.6365 | 1.9334 | |
| HCC1569 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 7825.011 | 0.6274 | 0.5715 | 1.9334 | |
| HCC1569 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7825.011 | 0.3585 | 0.1765 | 1.9334 | |
| HCC1569 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7825.011 | 0.2962 | 0.0659 | 1.9334 | |
| HCC1569 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7825.011 | 0.1889 | -0.1553 | 1.9334 | |
| HCC1569 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9347.011 | 1.0012 | 1.0015 | 1.6648 | |
| HCC1569 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9347.011 | 0.9766 | 0.9718 | 1.6648 | |
| HCC1569 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9347.011 | 1.0157 | 1.0188 | 1.6648 | |
| HCC1569 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9347.011 | 0.8888 | 0.8633 | 1.6648 | |
| HCC1569 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9347.011 | 0.8320 | 0.7908 | 1.6648 | |
| HCC1569 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9347.011 | 0.7461 | 0.6773 | 1.6648 | |
| HCC1569 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9347.011 | 0.4126 | 0.1752 | 1.6648 | |
| HCC1569 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9347.011 | 0.3504 | 0.0653 | 1.6648 | |
| HCC1569 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9347.011 | 0.2135 | -0.2089 | 1.6648 | |
| HCC1806 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7829.011 | 1.0150 | 1.0159 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7829.011 | 0.9742 | 0.9724 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7829.011 | 1.0049 | 1.0052 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7829.011 | 0.9082 | 0.8999 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7829.011 | 0.6777 | 0.6251 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 7829.011 | 0.3716 | 0.1795 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7829.011 | 0.2586 | -0.0279 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7829.011 | 0.0127 | -0.8049 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7829.011 | 0.0094 | -0.8339 | 1.8746 | |
| HCC1806 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9376.011 | 1.0556 | 1.0696 | 1.5809 |