Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | Olomoucine II | CDK1 | CDK | 26.7 | uM | 10996.147 | 0.5221 | -0.2916 | 0.6261 | |
| HCC2185 | TNBC | Luminal | Olomoucine II | CDK1 | CDK | 133 | uM | 10996.147 | 0.4639 | -0.4136 | 0.6261 | |
| HCC2185 | TNBC | Luminal | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 12192.147 | 0.9676 | 0.8867 | 0.5645 | |
| HCC2185 | TNBC | Luminal | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 12192.147 | 0.9861 | 0.9510 | 0.5645 | |
| HCC2185 | TNBC | Luminal | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 12192.147 | 1.0460 | 1.1657 | 0.5645 | |
| HCC2185 | TNBC | Luminal | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 12192.147 | 1.1009 | 1.3712 | 0.5645 | |
| HCC2185 | TNBC | Luminal | Olomoucine II | CDK1 | CDK | 0.213 | uM | 12192.147 | 1.0671 | 1.2437 | 0.5645 | |
| HCC2185 | TNBC | Luminal | Olomoucine II | CDK1 | CDK | 1.07 | uM | 12192.147 | 1.0064 | 1.0227 | 0.5645 | |
| HCC2185 | TNBC | Luminal | Olomoucine II | CDK1 | CDK | 5.33 | uM | 12192.147 | 0.8965 | 0.6479 | 0.5645 | |
| HCC2185 | TNBC | Luminal | Olomoucine II | CDK1 | CDK | 26.7 | uM | 12192.147 | 0.4765 | -0.4620 | 0.5645 | |
| HCC2185 | TNBC | Luminal | Olomoucine II | CDK1 | CDK | 133 | uM | 12192.147 | 0.3375 | -0.7080 | 0.5645 | |
| HCC3153 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 10937.147 | 1.0089 | 1.0141 | 1.2614 | |
| HCC3153 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 10937.147 | 1.0511 | 1.0806 | 1.2614 | |
| HCC3153 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 10937.147 | 1.0332 | 1.0525 | 1.2614 | |
| HCC3153 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 10937.147 | 1.1259 | 1.1971 | 1.2614 | |
| HCC3153 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 0.213 | uM | 10937.147 | 0.9593 | 0.9351 | 1.2614 | |
| HCC3153 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 1.07 | uM | 10937.147 | 0.8901 | 0.8237 | 1.2614 | |
| HCC3153 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 5.33 | uM | 10937.147 | 0.5666 | 0.2748 | 1.2614 | |
| HCC3153 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 26.7 | uM | 10937.147 | 0.0760 | -0.7408 | 1.2614 | |
| HCC3153 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 133 | uM | 10937.147 | 0.0268 | -0.8865 | 1.2614 | |
| HCC38 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 11850.147 | 0.9659 | 0.9674 | 2.1087 | |
| HCC38 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 11850.147 | 0.9240 | 0.9264 | 2.1087 | |
| HCC38 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 11850.147 | 0.9418 | 0.9440 | 2.1087 | |
| HCC38 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 11850.147 | 1.0082 | 1.0077 | 2.1087 | |
| HCC38 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.213 | uM | 11850.147 | 0.9397 | 0.9419 | 2.1087 |