Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 1.07 | uM | 11850.147 | 0.8587 | 0.8606 | 2.1087 | |
| HCC38 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 5.33 | uM | 11850.147 | 0.3635 | 0.2377 | 2.1087 | |
| HCC38 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 26.7 | uM | 11850.147 | 0.0522 | -0.5067 | 2.1087 | |
| HCC38 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 133 | uM | 11850.147 | 0.0497 | -0.5182 | 2.1087 | |
| HCC70 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 10873.147 | 0.9609 | 0.9394 | 1.2965 | |
| HCC70 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 10873.147 | 0.9551 | 0.9304 | 1.2965 | |
| HCC70 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 10873.147 | 0.9377 | 0.9033 | 1.2965 | |
| HCC70 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 10873.147 | 1.0140 | 1.0215 | 1.2965 | |
| HCC70 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 0.213 | uM | 10873.147 | 0.9415 | 0.9092 | 1.2965 | |
| HCC70 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 1.07 | uM | 10873.147 | 0.8875 | 0.8241 | 1.2965 | |
| HCC70 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 5.33 | uM | 10873.147 | 0.5654 | 0.2884 | 1.2965 | |
| HCC70 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 26.7 | uM | 10873.147 | 0.0128 | -0.9305 | 1.2965 | |
| HCC70 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 133 | uM | 10873.147 | 0.0070 | -0.9564 | 1.2965 | |
| HCC70 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 12400.147 | 0.9833 | 0.9735 | 1.2599 | |
| HCC70 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 12400.147 | 0.9449 | 0.9120 | 1.2599 | |
| HCC70 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 12400.147 | 0.9650 | 0.9443 | 1.2599 | |
| HCC70 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 12400.147 | 0.9839 | 0.9744 | 1.2599 | |
| HCC70 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 0.213 | uM | 12400.147 | 0.9575 | 0.9322 | 1.2599 | |
| HCC70 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 1.07 | uM | 12400.147 | 0.8886 | 0.8210 | 1.2599 | |
| HCC70 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 5.33 | uM | 12400.147 | 0.5635 | 0.2685 | 1.2599 | |
| HCC70 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 26.7 | uM | 12400.147 | 0.0092 | -0.9516 | 1.2599 | |
| HCC70 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 133 | uM | 12400.147 | 0.0080 | -0.9567 | 1.2599 | |
| Hs 578T | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 10694.147 | 1.0444 | 1.0368 | 2.3818 | |
| Hs 578T | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 10694.147 | 1.0037 | 1.0031 | 2.3818 | |
| Hs 578T | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 10694.147 | 0.9717 | 0.9760 | 2.3818 |