Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HBL-100 | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7429.066 | 1.0131 | 1.0109 | 2.3904 | |
| HBL-100 | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7429.066 | 0.9409 | 0.9497 | 2.3904 | |
| HBL-100 | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7429.066 | 0.9610 | 0.9670 | 2.3904 | |
| HBL-100 | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7429.066 | 0.9822 | 0.9850 | 2.3904 | |
| HBL-100 | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7429.066 | 0.9890 | 0.9908 | 2.3904 | |
| HBL-100 | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7429.066 | 0.9761 | 0.9799 | 2.3904 | |
| HBL-100 | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7429.066 | 0.9741 | 0.9781 | 2.3904 | |
| HBL-100 | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7429.066 | 0.9429 | 0.9514 | 2.3904 | |
| HBL-100 | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7429.066 | 0.3803 | 0.3347 | 2.3904 | |
| HCC1143 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7430.066 | 1.0109 | 1.0124 | 1.7623 | |
| HCC1143 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7430.066 | 1.0138 | 1.0157 | 1.7623 | |
| HCC1143 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7430.066 | 0.9788 | 0.9759 | 1.7623 | |
| HCC1143 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7430.066 | 0.9891 | 0.9876 | 1.7623 | |
| HCC1143 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7430.066 | 1.0212 | 1.0239 | 1.7623 | |
| HCC1143 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7430.066 | 1.0529 | 1.0594 | 1.7623 | |
| HCC1143 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7430.066 | 1.0203 | 1.0230 | 1.7623 | |
| HCC1143 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7430.066 | 0.9832 | 0.9809 | 1.7623 | |
| HCC1143 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7430.066 | 0.4252 | 0.2310 | 1.7623 | |
| HCC1187 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7431.066 | 0.9813 | 0.9684 | 1.1865 | |
| HCC1187 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7431.066 | 0.9694 | 0.9483 | 1.1865 | |
| HCC1187 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7431.066 | 0.9541 | 0.9224 | 1.1865 | |
| HCC1187 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7431.066 | 1.0233 | 1.0391 | 1.1865 | |
| HCC1187 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7431.066 | 1.0119 | 1.0200 | 1.1865 | |
| HCC1187 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7431.066 | 0.9499 | 0.9152 | 1.1865 | |
| HCC1187 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7431.066 | 0.9651 | 0.9410 | 1.1865 |