Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-549 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12305.147 | 0.9680 | 0.9776 | 2.8865 | |
| BT-549 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12305.147 | 0.9601 | 0.9720 | 2.8865 | |
| BT-549 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12305.147 | 0.9289 | 0.9495 | 2.8865 | |
| BT-549 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12305.147 | 0.7357 | 0.7982 | 2.8865 | |
| BT-549 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12305.147 | 0.3718 | 0.4197 | 2.8865 | |
| CAMA-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 10755.147 | 0.9298 | 0.7770 | 0.6156 | |
| CAMA-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 10755.147 | 0.9152 | 0.7319 | 0.6156 | |
| CAMA-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 10755.147 | 0.9612 | 0.8756 | 0.6156 | |
| CAMA-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 10755.147 | 0.9485 | 0.8355 | 0.6156 | |
| CAMA-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 10755.147 | 0.9967 | 0.9893 | 0.6156 | |
| CAMA-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 10755.147 | 1.0069 | 1.0226 | 0.6156 | |
| CAMA-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 10755.147 | 1.0532 | 1.1758 | 0.6156 | |
| CAMA-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 10755.147 | 0.9658 | 0.8901 | 0.6156 | |
| CAMA-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 10755.147 | 0.4345 | -0.4836 | 0.6156 | |
| CAMA-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12070.147 | 0.8780 | 0.7381 | 0.9269 | |
| CAMA-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12070.147 | 0.9137 | 0.8145 | 0.9269 | |
| CAMA-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 12070.147 | 0.8989 | 0.7826 | 0.9269 | |
| CAMA-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12070.147 | 0.9975 | 0.9947 | 0.9269 | |
| CAMA-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12070.147 | 1.0104 | 1.0226 | 0.9269 | |
| CAMA-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12070.147 | 0.8450 | 0.6676 | 0.9269 | |
| CAMA-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12070.147 | 1.0439 | 1.0948 | 0.9269 | |
| CAMA-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12070.147 | 0.7156 | 0.3939 | 0.9269 | |
| CAMA-1 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12070.147 | 0.1125 | -0.8106 | 0.9269 | |
| HCC1143 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12112.147 | 0.9103 | 0.9013 | 1.8559 | |
| HCC1143 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12112.147 | 0.8963 | 0.8854 | 1.8559 |