Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 66.7 | uM | 11854.147 | 0.5171 | 0.1866 | 1.2634 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12056.147 | 0.8972 | 0.7561 | 0.8344 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12056.147 | 0.8655 | 0.6822 | 0.8344 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 12056.147 | 0.9783 | 0.9481 | 0.8344 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12056.147 | 0.9319 | 0.8380 | 0.8344 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12056.147 | 0.9725 | 0.9342 | 0.8344 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12056.147 | 0.9358 | 0.8471 | 0.8344 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12056.147 | 1.0034 | 1.0081 | 0.8344 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12056.147 | 0.9003 | 0.7635 | 0.8344 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12056.147 | 0.2940 | -0.5388 | 0.8344 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12178.147 | 0.9961 | 0.9865 | 0.5795 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12178.147 | 0.9365 | 0.7860 | 0.5795 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 12178.147 | 0.9096 | 0.6984 | 0.5795 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12178.147 | 0.9754 | 0.9159 | 0.5795 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12178.147 | 1.0335 | 1.1172 | 0.5795 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12178.147 | 1.0090 | 1.0310 | 0.5795 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12178.147 | 1.0674 | 1.2382 | 0.5795 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12178.147 | 0.9368 | 0.7869 | 0.5795 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12178.147 | 0.4354 | -0.5237 | 0.5795 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12291.147 | 0.9074 | 0.7001 | 0.5980 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12291.147 | 0.9554 | 0.8529 | 0.5980 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 12291.147 | 1.0402 | 1.1362 | 0.5980 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12291.147 | 0.9400 | 0.8034 | 0.5980 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12291.147 | 0.9650 | 0.8843 | 0.5980 | |
| BT-474 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12291.147 | 0.9517 | 0.8411 | 0.5980 |