Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 10880.147 | 1.0213 | 1.0278 | 1.5262 | |
| AU565 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 10880.147 | 0.9542 | 0.9394 | 1.5262 | |
| AU565 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 10880.147 | 0.9215 | 0.8957 | 1.5262 | |
| AU565 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 10880.147 | 0.9295 | 0.9065 | 1.5262 | |
| AU565 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 10880.147 | 0.9819 | 0.9761 | 1.5262 | |
| AU565 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 10880.147 | 0.9085 | 0.8781 | 1.5262 | |
| AU565 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 10880.147 | 0.8612 | 0.8135 | 1.5262 | |
| AU565 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 10880.147 | 0.0264 | -0.8151 | 1.5262 | |
| BT-20 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 10581.147 | 0.9554 | 0.9135 | 1.0319 | |
| BT-20 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 10581.147 | 0.9669 | 0.9358 | 1.0319 | |
| BT-20 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 10581.147 | 0.9637 | 0.9296 | 1.0319 | |
| BT-20 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 10581.147 | 1.0611 | 1.1183 | 1.0319 | |
| BT-20 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.107 | uM | 10581.147 | 1.0111 | 1.0215 | 1.0319 | |
| BT-20 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.533 | uM | 10581.147 | 0.9807 | 0.9625 | 1.0319 | |
| BT-20 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 2.67 | uM | 10581.147 | 0.9962 | 0.9926 | 1.0319 | |
| BT-20 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 13.3 | uM | 10581.147 | 1.0025 | 1.0049 | 1.0319 | |
| BT-20 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 66.7 | uM | 10581.147 | 0.4894 | 0.0007 | 1.0319 | |
| BT-20 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 11854.147 | 0.9780 | 0.9650 | 1.2634 | |
| BT-20 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 11854.147 | 0.9925 | 0.9882 | 1.2634 | |
| BT-20 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 11854.147 | 0.9553 | 0.9289 | 1.2634 | |
| BT-20 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 11854.147 | 0.9232 | 0.8774 | 1.2634 | |
| BT-20 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.107 | uM | 11854.147 | 0.9753 | 0.9608 | 1.2634 | |
| BT-20 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.533 | uM | 11854.147 | 0.9149 | 0.8640 | 1.2634 | |
| BT-20 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 2.67 | uM | 11854.147 | 1.0016 | 1.0025 | 1.2634 | |
| BT-20 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 13.3 | uM | 11854.147 | 0.9872 | 0.9796 | 1.2634 |