Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184A1 | NM | Basal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12509.147 | 1.0548 | 1.0904 | 1.2058 | |
| 184A1 | NM | Basal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12509.147 | 1.0585 | 1.0966 | 1.2058 | |
| 184A1 | NM | Basal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12509.147 | 0.9305 | 0.8840 | 1.2058 | |
| 184A1 | NM | Basal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12509.147 | 0.9234 | 0.8721 | 1.2058 | |
| 184A1 | NM | Basal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12509.147 | 0.4218 | -0.0226 | 1.2058 | |
| 184A1 | NM | Basal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12509.147 | 0.0363 | -0.8721 | 1.2058 | |
| 184B5 | NM | Basal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12566.147 | 0.9797 | 0.9748 | 1.6169 | |
| 184B5 | NM | Basal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12566.147 | 1.0301 | 1.0370 | 1.6169 | |
| 184B5 | NM | Basal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 12566.147 | 0.9918 | 0.9898 | 1.6169 | |
| 184B5 | NM | Basal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12566.147 | 1.0249 | 1.0307 | 1.6169 | |
| 184B5 | NM | Basal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12566.147 | 1.0209 | 1.0257 | 1.6169 | |
| 184B5 | NM | Basal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12566.147 | 0.9382 | 0.9226 | 1.6169 | |
| 184B5 | NM | Basal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12566.147 | 0.7664 | 0.6966 | 1.6169 | |
| 184B5 | NM | Basal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12566.147 | 0.2688 | -0.1126 | 1.6169 | |
| 184B5 | NM | Basal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12566.147 | 0.0131 | -0.8630 | 1.6169 | |
| 600MPE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12224.147 | 0.9679 | 0.9256 | 0.8621 | |
| 600MPE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12224.147 | 0.9808 | 0.9555 | 0.8621 | |
| 600MPE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 12224.147 | 1.0007 | 1.0016 | 0.8621 | |
| 600MPE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12224.147 | 1.0067 | 1.0155 | 0.8621 | |
| 600MPE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12224.147 | 1.0151 | 1.0350 | 0.8621 | |
| 600MPE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12224.147 | 1.0243 | 1.0565 | 0.8621 | |
| 600MPE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12224.147 | 1.0454 | 1.1057 | 0.8621 | |
| 600MPE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12224.147 | 0.7840 | 0.5081 | 0.8621 | |
| 600MPE | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12224.147 | 0.0510 | -0.9366 | 0.8621 | |
| AU565 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 10880.147 | 0.9277 | 0.9040 | 1.5262 |