Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.000427 | uM | 7465.066 | 0.9100 | 0.8560 | 1.2627 | |
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.00213 | uM | 7465.066 | 1.0172 | 1.0272 | 1.2627 | |
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0107 | uM | 7465.066 | 1.0372 | 1.0588 | 1.2627 | |
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0533 | uM | 7465.066 | 1.0372 | 1.0588 | 1.2627 | |
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.267 | uM | 7465.066 | 0.9240 | 0.8786 | 1.2627 | |
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 1.33 | uM | 7465.066 | 0.9773 | 0.9639 | 1.2627 | |
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 6.67 | uM | 7465.066 | 0.8969 | 0.8349 | 1.2627 | |
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 33.3 | uM | 7465.066 | 0.7680 | 0.6227 | 1.2627 | |
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7466.066 | 1.0412 | 1.0876 | 0.9420 | |
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.000427 | uM | 7466.066 | 1.0744 | 1.1582 | 0.9420 | |
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.00213 | uM | 7466.066 | 1.0364 | 1.0774 | 0.9420 | |
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0107 | uM | 7466.066 | 1.0893 | 1.1902 | 0.9420 | |
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0533 | uM | 7466.066 | 1.0854 | 1.1819 | 0.9420 | |
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.267 | uM | 7466.066 | 1.0064 | 1.0135 | 0.9420 | |
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 1.33 | uM | 7466.066 | 1.0640 | 1.1362 | 0.9420 | |
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 6.67 | uM | 7466.066 | 0.7506 | 0.4749 | 0.9420 | |
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 33.3 | uM | 7466.066 | 0.5518 | 0.0639 | 0.9420 | |
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7467.066 | 1.0113 | 1.0189 | 1.1956 | |
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.000427 | uM | 7467.066 | 0.9513 | 0.9182 | 1.1956 | |
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.00213 | uM | 7467.066 | 1.0315 | 1.0526 | 1.1956 | |
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0107 | uM | 7467.066 | 0.9893 | 0.9821 | 1.1956 | |
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0533 | uM | 7467.066 | 0.9580 | 0.9295 | 1.1956 | |
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.267 | uM | 7467.066 | 0.9991 | 0.9985 | 1.1956 | |
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 1.33 | uM | 7467.066 | 1.0228 | 1.0381 | 1.1956 | |
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 6.67 | uM | 7467.066 | 0.8500 | 0.7458 | 1.1956 |