Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 7462.066 | 0.9923 | 0.9728 | 0.5644 | |
| HCC2185 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 7462.066 | 0.9830 | 0.9402 | 0.5644 | |
| HCC2185 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 7462.066 | 0.9412 | 0.7965 | 0.5644 | |
| HCC2185 | TNBC | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 7462.066 | 0.9887 | 0.9600 | 0.5644 | |
| HCC2185 | TNBC | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 7462.066 | 0.8891 | 0.6240 | 0.5644 | |
| HCC2185 | TNBC | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 7462.066 | 0.8181 | 0.4013 | 0.5644 | |
| HCC2185 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7463.066 | 1.0303 | 1.1105 | 0.5542 | |
| HCC2185 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 7463.066 | 0.9866 | 0.9520 | 0.5542 | |
| HCC2185 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 7463.066 | 1.0085 | 1.0307 | 0.5542 | |
| HCC2185 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 7463.066 | 0.9506 | 0.8252 | 0.5542 | |
| HCC2185 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 7463.066 | 1.0268 | 1.0976 | 0.5542 | |
| HCC2185 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 7463.066 | 1.0283 | 1.1031 | 0.5542 | |
| HCC2185 | TNBC | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 7463.066 | 0.9573 | 0.8484 | 0.5542 | |
| HCC2185 | TNBC | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 7463.066 | 0.7957 | 0.3242 | 0.5542 | |
| HCC2185 | TNBC | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 7463.066 | 0.7055 | 0.0659 | 0.5542 | |
| HCC2185 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7464.066 | 1.0653 | 1.2083 | 0.6384 | |
| HCC2185 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 7464.066 | 1.0172 | 1.0540 | 0.6384 | |
| HCC2185 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 7464.066 | 1.0213 | 1.0671 | 0.6384 | |
| HCC2185 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 7464.066 | 1.0650 | 1.2074 | 0.6384 | |
| HCC2185 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 7464.066 | 1.0008 | 1.0026 | 0.6384 | |
| HCC2185 | TNBC | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 7464.066 | 1.0284 | 1.0896 | 0.6384 | |
| HCC2185 | TNBC | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 7464.066 | 1.0213 | 1.0671 | 0.6384 | |
| HCC2185 | TNBC | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 7464.066 | 0.9262 | 0.7735 | 0.6384 | |
| HCC2185 | TNBC | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 7464.066 | 0.8136 | 0.4476 | 0.6384 | |
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7465.066 | 1.0875 | 1.1374 | 1.2627 |