Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.267 | uM | 7430.066 | 1.0125 | 1.0142 | 1.7623 | |
| HCC1143 | TNBC | Basal A | AG1024 | IGF1R | RTK | 1.33 | uM | 7430.066 | 0.9981 | 0.9978 | 1.7623 | |
| HCC1143 | TNBC | Basal A | AG1024 | IGF1R | RTK | 6.67 | uM | 7430.066 | 0.9333 | 0.9232 | 1.7623 | |
| HCC1143 | TNBC | Basal A | AG1024 | IGF1R | RTK | 33.3 | uM | 7430.066 | 0.5553 | 0.4325 | 1.7623 | |
| HCC1187 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7431.066 | 1.0122 | 1.0206 | 1.1865 | |
| HCC1187 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.000427 | uM | 7431.066 | 0.9448 | 0.9065 | 1.1865 | |
| HCC1187 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.00213 | uM | 7431.066 | 0.9904 | 0.9839 | 1.1865 | |
| HCC1187 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0107 | uM | 7431.066 | 1.0151 | 1.0254 | 1.1865 | |
| HCC1187 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0533 | uM | 7431.066 | 1.0225 | 1.0379 | 1.1865 | |
| HCC1187 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.267 | uM | 7431.066 | 0.9716 | 0.9520 | 1.1865 | |
| HCC1187 | TNBC | Basal A | AG1024 | IGF1R | RTK | 1.33 | uM | 7431.066 | 1.0106 | 1.0178 | 1.1865 | |
| HCC1187 | TNBC | Basal A | AG1024 | IGF1R | RTK | 6.67 | uM | 7431.066 | 0.8664 | 0.7723 | 1.1865 | |
| HCC1187 | TNBC | Basal A | AG1024 | IGF1R | RTK | 33.3 | uM | 7431.066 | 0.7687 | 0.6023 | 1.1865 | |
| HCC1187 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7432.066 | 1.0395 | 1.0791 | 0.9987 | |
| HCC1187 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.000427 | uM | 7432.066 | 1.0567 | 1.1135 | 0.9987 | |
| HCC1187 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.00213 | uM | 7432.066 | 1.0339 | 1.0680 | 0.9987 | |
| HCC1187 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0107 | uM | 7432.066 | 0.9960 | 0.9920 | 0.9987 | |
| HCC1187 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0533 | uM | 7432.066 | 1.0020 | 1.0041 | 0.9987 | |
| HCC1187 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.267 | uM | 7432.066 | 1.0431 | 1.0863 | 0.9987 | |
| HCC1187 | TNBC | Basal A | AG1024 | IGF1R | RTK | 1.33 | uM | 7432.066 | 1.0115 | 1.0230 | 0.9987 | |
| HCC1187 | TNBC | Basal A | AG1024 | IGF1R | RTK | 6.67 | uM | 7432.066 | 0.9125 | 0.8248 | 0.9987 | |
| HCC1187 | TNBC | Basal A | AG1024 | IGF1R | RTK | 33.3 | uM | 7432.066 | 0.8293 | 0.6582 | 0.9987 | |
| HCC1187 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7433.066 | 1.0530 | 1.0984 | 1.0755 | |
| HCC1187 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.000427 | uM | 7433.066 | 1.0296 | 1.0550 | 1.0755 | |
| HCC1187 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.00213 | uM | 7433.066 | 1.0438 | 1.0813 | 1.0755 |