Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14179.189 | 0.9602 | 0.8223 | 0.4365 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14179.189 | 0.9602 | 0.8223 | 0.4365 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14179.189 | 0.3296 | -0.8427 | 0.4365 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14179.189 | 0.3296 | -0.8427 | 0.4365 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14179.189 | 0.0097 | -1.0000 | 0.4365 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14179.189 | 0.0097 | -1.0000 | 0.4365 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14179.189 | 0.0104 | -0.9999 | 0.4365 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14179.189 | 0.0104 | -0.9999 | 0.4365 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14179.189 | 0.9910 | 0.9588 | 0.4365 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14179.189 | 0.9910 | 0.9588 | 0.4365 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14293.189 | 1.0024 | 1.0073 | 0.6707 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14293.189 | 1.0024 | 1.0073 | 0.6707 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14293.189 | 1.0421 | 1.1268 | 0.6707 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14293.189 | 1.0421 | 1.1268 | 0.6707 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14293.189 | 1.0186 | 1.0557 | 0.6707 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14293.189 | 1.0186 | 1.0557 | 0.6707 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14293.189 | 1.0131 | 1.0393 | 0.6707 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14293.189 | 1.0131 | 1.0393 | 0.6707 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14293.189 | 1.0078 | 1.0233 | 0.6707 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14293.189 | 1.0078 | 1.0233 | 0.6707 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14293.189 | 0.7504 | 0.3034 | 0.6707 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14293.189 | 0.7504 | 0.3034 | 0.6707 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14293.189 | 1.1060 | 1.3241 | 0.6707 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14293.189 | 1.1060 | 1.3241 | 0.6707 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14293.189 | 1.0927 | 1.2825 | 0.6707 |