Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14652.189 | 0.4320 | 0.3954 | 2.3317 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14652.189 | 0.4320 | 0.3954 | 2.3317 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14652.189 | 0.0071 | -0.7611 | 2.3317 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14652.189 | 0.0071 | -0.7611 | 2.3317 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14652.189 | 0.0094 | -0.7293 | 2.3317 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14652.189 | 0.0094 | -0.7293 | 2.3317 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14652.189 | 0.0085 | -0.7406 | 2.3317 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14652.189 | 0.0085 | -0.7406 | 2.3317 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 11057.145 | 1.0584 | 1.0299 | 3.8266 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 11057.145 | 1.0584 | 1.0299 | 3.8266 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 11057.145 | 1.0010 | 1.0005 | 3.8266 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 11057.145 | 1.0010 | 1.0005 | 3.8266 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 11057.145 | 1.0858 | 1.0435 | 3.8266 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 11057.145 | 1.0858 | 1.0435 | 3.8266 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 11057.145 | 0.9484 | 0.9725 | 3.8266 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 11057.145 | 0.9484 | 0.9725 | 3.8266 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11057.145 | 0.0488 | -0.0915 | 3.8266 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11057.145 | 0.0488 | -0.0915 | 3.8266 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11057.145 | 0.0161 | -0.3203 | 3.8266 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11057.145 | 0.0161 | -0.3203 | 3.8266 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11057.145 | 0.0013 | -0.6499 | 3.8266 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11057.145 | 0.0013 | -0.6499 | 3.8266 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11057.145 | 0.0199 | -0.2815 | 3.8266 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11057.145 | 0.0199 | -0.2815 | 3.8266 | |
| SUM159PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11057.145 | 0.0004 | -0.7373 | 3.8266 |