Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10939.145 | 0.9805 | 0.9764 | 1.6558 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10939.145 | 0.9552 | 0.9454 | 1.6558 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10939.145 | 0.9552 | 0.9454 | 1.6558 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10939.145 | 0.9887 | 0.9863 | 1.6558 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10939.145 | 0.9887 | 0.9863 | 1.6558 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10939.145 | 0.9823 | 0.9786 | 1.6558 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10939.145 | 0.9823 | 0.9786 | 1.6558 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10939.145 | 0.6766 | 0.5796 | 1.6558 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10939.145 | 0.6766 | 0.5796 | 1.6558 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10939.145 | 0.0198 | -0.8130 | 1.6558 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10939.145 | 0.0198 | -0.8130 | 1.6558 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10939.145 | 0.0104 | -0.8728 | 1.6558 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10939.145 | 0.0104 | -0.8728 | 1.6558 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10939.145 | 0.0202 | -0.8106 | 1.6558 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10939.145 | 0.0202 | -0.8106 | 1.6558 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10939.145 | 0.0127 | -0.8571 | 1.6558 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10939.145 | 0.0127 | -0.8571 | 1.6558 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14179.189 | 1.0239 | 1.1114 | 0.4365 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14179.189 | 1.0239 | 1.1114 | 0.4365 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14179.189 | 1.0042 | 1.0195 | 0.4365 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14179.189 | 1.0042 | 1.0195 | 0.4365 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14179.189 | 0.9949 | 0.9767 | 0.4365 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14179.189 | 0.9949 | 0.9767 | 0.4365 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14179.189 | 0.9837 | 0.9259 | 0.4365 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14179.189 | 0.9837 | 0.9259 | 0.4365 |