Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14293.189 | 1.0927 | 1.2825 | 0.6707 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14293.189 | 1.1216 | 1.3731 | 0.6707 | |
| T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14293.189 | 1.1216 | 1.3731 | 0.6707 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12608.17 | 0.9671 | 0.9388 | 1.0776 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12608.17 | 0.9671 | 0.9388 | 1.0776 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12608.17 | 0.9454 | 0.8985 | 1.0776 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12608.17 | 0.9454 | 0.8985 | 1.0776 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12608.17 | 0.9797 | 0.9623 | 1.0776 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12608.17 | 0.9797 | 0.9623 | 1.0776 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12608.17 | 0.9499 | 0.9068 | 1.0776 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12608.17 | 0.9499 | 0.9068 | 1.0776 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12608.17 | 0.8955 | 0.8053 | 1.0776 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12608.17 | 0.8955 | 0.8053 | 1.0776 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12608.17 | 0.0215 | -0.9432 | 1.0776 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12608.17 | 0.0215 | -0.9432 | 1.0776 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12608.17 | 0.0219 | -0.9422 | 1.0776 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12608.17 | 0.0219 | -0.9422 | 1.0776 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12608.17 | 0.0202 | -0.9465 | 1.0776 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12608.17 | 0.0202 | -0.9465 | 1.0776 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12608.17 | 0.0165 | -0.9557 | 1.0776 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12608.17 | 0.0165 | -0.9557 | 1.0776 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14182.189 | 0.9926 | 0.9578 | 0.3468 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14182.189 | 0.9926 | 0.9578 | 0.3468 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14182.189 | 0.9691 | 0.8267 | 0.3468 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14182.189 | 0.9691 | 0.8267 | 0.3468 |