Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12192.145 | 0.0735 | -0.9962 | 0.4175 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12192.145 | 0.0906 | -0.9937 | 0.4175 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12192.145 | 0.0906 | -0.9937 | 0.4175 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10577.145 | 1.0125 | 1.0259 | 0.9676 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10577.145 | 1.0125 | 1.0259 | 0.9676 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10577.145 | 0.9422 | 0.8807 | 0.9676 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10577.145 | 0.9422 | 0.8807 | 0.9676 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10577.145 | 0.9793 | 0.9572 | 0.9676 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10577.145 | 0.9793 | 0.9572 | 0.9676 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10577.145 | 0.9602 | 0.9177 | 0.9676 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10577.145 | 0.9602 | 0.9177 | 0.9676 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10577.145 | 0.9366 | 0.8690 | 0.9676 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10577.145 | 0.9366 | 0.8690 | 0.9676 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10577.145 | 0.0540 | -0.9020 | 0.9676 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10577.145 | 0.0540 | -0.9020 | 0.9676 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10577.145 | 0.0189 | -0.9670 | 0.9676 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10577.145 | 0.0189 | -0.9670 | 0.9676 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10577.145 | 0.0184 | -0.9677 | 0.9676 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10577.145 | 0.0184 | -0.9677 | 0.9676 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10577.145 | 0.0173 | -0.9699 | 0.9676 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10577.145 | 0.0173 | -0.9699 | 0.9676 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10937.145 | 0.9874 | 0.9791 | 1.2098 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10937.145 | 0.9874 | 0.9791 | 1.2098 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10937.145 | 0.9943 | 0.9906 | 1.2098 | |
| HCC3153 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10937.145 | 0.9943 | 0.9906 | 1.2098 |