Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | Nelfinavir | 0.0533 | uM | 13733.174 | 0.9527 | 0.8186 | 0.5093 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 0.267 | uM | 13733.174 | 0.9417 | 0.7776 | 0.5093 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 1.33 | uM | 13733.174 | 0.9630 | 0.8574 | 0.5093 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 6.67 | uM | 13733.174 | 0.8716 | 0.5271 | 0.5093 | |||
| HCC3153 | TNBC | Basal A | Nelfinavir | 33.3 | uM | 13733.174 | 0.0407 | -0.9963 | 0.5093 | |||
| HCC38 | TNBC | Basal B | Nelfinavir | 0.0000853 | uM | 12617.174 | 0.9955 | 0.9944 | 1.5935 | |||
| HCC38 | TNBC | Basal B | Nelfinavir | 0.000427 | uM | 12617.174 | 0.9938 | 0.9922 | 1.5935 | |||
| HCC38 | TNBC | Basal B | Nelfinavir | 0.00213 | uM | 12617.174 | 0.9852 | 0.9813 | 1.5935 | |||
| HCC38 | TNBC | Basal B | Nelfinavir | 0.0107 | uM | 12617.174 | 1.0184 | 1.0230 | 1.5935 | |||
| HCC38 | TNBC | Basal B | Nelfinavir | 0.0533 | uM | 12617.174 | 1.0072 | 1.0090 | 1.5935 | |||
| HCC38 | TNBC | Basal B | Nelfinavir | 0.267 | uM | 12617.174 | 0.9697 | 0.9618 | 1.5935 | |||
| HCC38 | TNBC | Basal B | Nelfinavir | 1.33 | uM | 12617.174 | 0.9799 | 0.9746 | 1.5935 | |||
| HCC38 | TNBC | Basal B | Nelfinavir | 6.67 | uM | 12617.174 | 0.9599 | 0.9492 | 1.5935 | |||
| HCC38 | TNBC | Basal B | Nelfinavir | 33.3 | uM | 12617.174 | 0.0796 | -0.5913 | 1.5935 | |||
| HCC70 | TNBC | Basal A | Nelfinavir | 0.0000853 | uM | 12714.174 | 0.9726 | 0.8387 | 0.3306 | |||
| HCC70 | TNBC | Basal A | Nelfinavir | 0.000427 | uM | 12714.174 | 0.9370 | 0.6426 | 0.3306 | |||
| HCC70 | TNBC | Basal A | Nelfinavir | 0.00213 | uM | 12714.174 | 0.9670 | 0.8071 | 0.3306 | |||
| HCC70 | TNBC | Basal A | Nelfinavir | 0.0107 | uM | 12714.174 | 0.9546 | 0.7379 | 0.3306 | |||
| HCC70 | TNBC | Basal A | Nelfinavir | 0.0533 | uM | 12714.174 | 0.9720 | 0.8353 | 0.3306 | |||
| HCC70 | TNBC | Basal A | Nelfinavir | 0.267 | uM | 12714.174 | 0.9529 | 0.7282 | 0.3306 | |||
| HCC70 | TNBC | Basal A | Nelfinavir | 1.33 | uM | 12714.174 | 0.9848 | 0.9094 | 0.3306 | |||
| HCC70 | TNBC | Basal A | Nelfinavir | 6.67 | uM | 12714.174 | 0.9760 | 0.8585 | 0.3306 | |||
| HCC70 | TNBC | Basal A | Nelfinavir | 33.3 | uM | 12714.174 | 0.0162 | -1.0000 | 0.3306 | |||
| Hs 578T | TNBC | Basal B | Nelfinavir | 0.0000853 | uM | 12622.174 | 1.0209 | 1.0170 | 2.4358 | |||
| Hs 578T | TNBC | Basal B | Nelfinavir | 0.000427 | uM | 12622.174 | 0.9946 | 0.9956 | 2.4358 |