Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10996.145 | 0.8796 | 0.6009 | 0.5765 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10996.145 | 0.8796 | 0.6009 | 0.5765 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10996.145 | 0.2141 | -0.8620 | 0.5765 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10996.145 | 0.2141 | -0.8620 | 0.5765 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10996.145 | 0.1234 | -0.9470 | 0.5765 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10996.145 | 0.1234 | -0.9470 | 0.5765 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10996.145 | 0.0668 | -0.9817 | 0.5765 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10996.145 | 0.0668 | -0.9817 | 0.5765 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10996.145 | 0.0543 | -0.9872 | 0.5765 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10996.145 | 0.0543 | -0.9872 | 0.5765 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12192.145 | 1.0106 | 1.0511 | 0.4175 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12192.145 | 1.0106 | 1.0511 | 0.4175 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12192.145 | 1.0015 | 1.0072 | 0.4175 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12192.145 | 1.0015 | 1.0072 | 0.4175 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12192.145 | 0.9500 | 0.7689 | 0.4175 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12192.145 | 0.9500 | 0.7689 | 0.4175 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12192.145 | 0.9799 | 0.9048 | 0.4175 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12192.145 | 0.9799 | 0.9048 | 0.4175 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12192.145 | 1.0019 | 1.0092 | 0.4175 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12192.145 | 1.0019 | 1.0092 | 0.4175 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12192.145 | 0.2556 | -0.9238 | 0.4175 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12192.145 | 0.2556 | -0.9238 | 0.4175 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12192.145 | 0.1473 | -0.9797 | 0.4175 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12192.145 | 0.1473 | -0.9797 | 0.4175 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12192.145 | 0.0735 | -0.9962 | 0.4175 |