Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14209.189 | 0.9493 | 0.9490 | 2.0117 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14209.189 | 0.9155 | 0.9141 | 2.0117 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14209.189 | 0.9155 | 0.9141 | 2.0117 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14209.189 | 0.9485 | 0.9482 | 2.0117 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14209.189 | 0.9485 | 0.9482 | 2.0117 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14209.189 | 0.9576 | 0.9574 | 2.0117 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14209.189 | 0.9576 | 0.9574 | 2.0117 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14209.189 | 0.9647 | 0.9645 | 2.0117 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14209.189 | 0.9647 | 0.9645 | 2.0117 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14209.189 | 0.3068 | 0.1116 | 2.0117 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14209.189 | 0.3068 | 0.1116 | 2.0117 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14209.189 | 0.0073 | -0.8270 | 2.0117 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14209.189 | 0.0073 | -0.8270 | 2.0117 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14209.189 | 0.2478 | -0.0003 | 2.0117 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14209.189 | 0.2478 | -0.0003 | 2.0117 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14209.189 | 0.9399 | 0.9393 | 2.0117 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14209.189 | 0.9399 | 0.9393 | 2.0117 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10996.145 | 0.9583 | 0.8576 | 0.5765 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10996.145 | 0.9583 | 0.8576 | 0.5765 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10996.145 | 0.9508 | 0.8325 | 0.5765 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10996.145 | 0.9508 | 0.8325 | 0.5765 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10996.145 | 0.9811 | 0.9349 | 0.5765 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10996.145 | 0.9811 | 0.9349 | 0.5765 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10996.145 | 0.9838 | 0.9440 | 0.5765 | |
| HCC2185 | TNBC | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10996.145 | 0.9838 | 0.9440 | 0.5765 |