Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10880.145 | 0.0321 | -0.8055 | 1.4751 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10880.145 | 0.0321 | -0.8055 | 1.4751 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10880.145 | 0.0169 | -0.8742 | 1.4751 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10880.145 | 0.0169 | -0.8742 | 1.4751 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10880.145 | 0.0225 | -0.8475 | 1.4751 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10880.145 | 0.0225 | -0.8475 | 1.4751 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10880.145 | 0.0198 | -0.8600 | 1.4751 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10880.145 | 0.0198 | -0.8600 | 1.4751 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14113.189 | 1.0063 | 1.0086 | 1.4645 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14113.189 | 1.0063 | 1.0086 | 1.4645 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14113.189 | 0.9736 | 0.9638 | 1.4645 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14113.189 | 0.9736 | 0.9638 | 1.4645 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14113.189 | 0.9939 | 0.9917 | 1.4645 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14113.189 | 0.9939 | 0.9917 | 1.4645 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14113.189 | 0.9771 | 0.9686 | 1.4645 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14113.189 | 0.9771 | 0.9686 | 1.4645 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14113.189 | 0.9836 | 0.9776 | 1.4645 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14113.189 | 0.9836 | 0.9776 | 1.4645 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14113.189 | 0.1290 | -0.5059 | 1.4645 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14113.189 | 0.1290 | -0.5059 | 1.4645 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14113.189 | 0.0138 | -0.8928 | 1.4645 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14113.189 | 0.0138 | -0.8928 | 1.4645 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14113.189 | 0.0142 | -0.8904 | 1.4645 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14113.189 | 0.0142 | -0.8904 | 1.4645 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14113.189 | 0.9707 | 0.9598 | 1.4645 |