Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14197.189 | 0.9374 | 0.9071 | 1.3593 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14197.189 | 0.9792 | 0.9693 | 1.3593 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14197.189 | 0.9792 | 0.9693 | 1.3593 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14197.189 | 0.9947 | 0.9922 | 1.3593 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14197.189 | 0.9947 | 0.9922 | 1.3593 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14197.189 | 0.9696 | 0.9551 | 1.3593 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14197.189 | 0.9696 | 0.9551 | 1.3593 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14197.189 | 0.6530 | 0.4617 | 1.3593 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14197.189 | 0.6530 | 0.4617 | 1.3593 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14197.189 | 0.1332 | -0.5461 | 1.3593 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14197.189 | 0.1332 | -0.5461 | 1.3593 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14197.189 | 0.3471 | -0.0819 | 1.3593 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14197.189 | 0.3471 | -0.0819 | 1.3593 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14197.189 | 0.3563 | -0.0639 | 1.3593 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14197.189 | 0.3563 | -0.0639 | 1.3593 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10880.145 | 0.9775 | 0.9694 | 1.4751 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10880.145 | 0.9775 | 0.9694 | 1.4751 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10880.145 | 0.9898 | 0.9862 | 1.4751 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10880.145 | 0.9898 | 0.9862 | 1.4751 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10880.145 | 0.9750 | 0.9660 | 1.4751 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10880.145 | 0.9750 | 0.9660 | 1.4751 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10880.145 | 0.9353 | 0.9114 | 1.4751 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10880.145 | 0.9353 | 0.9114 | 1.4751 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10880.145 | 0.6104 | 0.4312 | 1.4751 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10880.145 | 0.6104 | 0.4312 | 1.4751 |