Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | Methylglyoxal | 17.3 | uM | 13123.184 | 0.7565 | 0.2758 | 0.6208 | |||
| SUM149PT | TNBC | Basal B | Methylglyoxal | 86.4 | uM | 13123.184 | 0.9710 | 0.9075 | 0.6208 | |||
| SUM149PT | TNBC | Basal B | Methylglyoxal | 432 | uM | 13123.184 | 0.5482 | -0.2406 | 0.6208 | |||
| SUM149PT | TNBC | Basal B | Methylglyoxal | 2160 | uM | 13123.184 | 0.0709 | -0.9719 | 0.6208 | |||
| SUM149PT | TNBC | Basal B | Methylglyoxal | 10800 | uM | 13123.184 | 0.0034 | -0.9998 | 0.6208 | |||
| SUM149PT | TNBC | Basal B | Methylglyoxal | 54000 | uM | 13123.184 | 0.0005 | -1.0000 | 0.6208 | |||
| SUM159PT | TNBC | Basal B | Methylglyoxal | 0.138 | uM | 13054.184 | 1.0476 | 1.0332 | 2.8248 | |||
| SUM159PT | TNBC | Basal B | Methylglyoxal | 0.691 | uM | 13054.184 | 0.8880 | 0.9176 | 2.8248 | |||
| SUM159PT | TNBC | Basal B | Methylglyoxal | 3.46 | uM | 13054.184 | 1.0103 | 1.0073 | 2.8248 | |||
| SUM159PT | TNBC | Basal B | Methylglyoxal | 17.3 | uM | 13054.184 | 0.2512 | 0.2264 | 2.8248 | |||
| SUM159PT | TNBC | Basal B | Methylglyoxal | 86.4 | uM | 13054.184 | 0.9901 | 0.9930 | 2.8248 | |||
| SUM159PT | TNBC | Basal B | Methylglyoxal | 432 | uM | 13054.184 | 0.0528 | -0.2938 | 2.8248 | |||
| SUM159PT | TNBC | Basal B | Methylglyoxal | 2160 | uM | 13054.184 | 0.0138 | -0.5615 | 2.8248 | |||
| SUM159PT | TNBC | Basal B | Methylglyoxal | 10800 | uM | 13054.184 | 0.0022 | -0.7721 | 2.8248 | |||
| SUM159PT | TNBC | Basal B | Methylglyoxal | 54000 | uM | 13054.184 | 0.0004 | -0.8767 | 2.8248 | |||
| SUM185PE | TNBC | Luminal | Methylglyoxal | 0.138 | uM | 13619.184 | 0.9618 | 0.9136 | 0.8825 | |||
| SUM185PE | TNBC | Luminal | Methylglyoxal | 0.691 | uM | 13619.184 | 0.9743 | 0.9419 | 0.8825 | |||
| SUM185PE | TNBC | Luminal | Methylglyoxal | 3.46 | uM | 13619.184 | 0.9619 | 0.9138 | 0.8825 | |||
| SUM185PE | TNBC | Luminal | Methylglyoxal | 17.3 | uM | 13619.184 | 1.0032 | 1.0073 | 0.8825 | |||
| SUM185PE | TNBC | Luminal | Methylglyoxal | 86.4 | uM | 13619.184 | 0.9098 | 0.7968 | 0.8825 | |||
| SUM185PE | TNBC | Luminal | Methylglyoxal | 432 | uM | 13619.184 | 0.9691 | 0.9301 | 0.8825 | |||
| SUM185PE | TNBC | Luminal | Methylglyoxal | 2160 | uM | 13619.184 | 0.2124 | -0.6544 | 0.8825 | |||
| SUM185PE | TNBC | Luminal | Methylglyoxal | 10800 | uM | 13619.184 | 0.2238 | -0.6332 | 0.8825 | |||
| SUM185PE | TNBC | Luminal | Methylglyoxal | 54000 | uM | 13619.184 | 0.9410 | 0.8669 | 0.8825 | |||
| SUM229PE | TNBC | - | Methylglyoxal | 0.138 | uM | 13062.184 | 0.9492 | 0.9424 | 1.7868 |