Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM229PE | TNBC | - | Methylglyoxal | 0.691 | uM | 13062.184 | 0.9086 | 0.8956 | 1.7868 | |||
| SUM229PE | TNBC | - | Methylglyoxal | 3.46 | uM | 13062.184 | 0.9289 | 0.9192 | 1.7868 | |||
| SUM229PE | TNBC | - | Methylglyoxal | 17.3 | uM | 13062.184 | 0.9038 | 0.8900 | 1.7868 | |||
| SUM229PE | TNBC | - | Methylglyoxal | 86.4 | uM | 13062.184 | 0.9160 | 0.9041 | 1.7868 | |||
| SUM229PE | TNBC | - | Methylglyoxal | 432 | uM | 13062.184 | 0.7030 | 0.6420 | 1.7868 | |||
| SUM229PE | TNBC | - | Methylglyoxal | 2160 | uM | 13062.184 | 0.1515 | -0.3044 | 1.7868 | |||
| SUM229PE | TNBC | - | Methylglyoxal | 10800 | uM | 13062.184 | 0.0127 | -0.8262 | 1.7868 | |||
| SUM229PE | TNBC | - | Methylglyoxal | 54000 | uM | 13062.184 | 0.0058 | -0.8881 | 1.7868 | |||
| SUM229PE | TNBC | - | Methylglyoxal | 0.138 | uM | 13201.184 | 0.9786 | 0.9678 | 1.3314 | |||
| SUM229PE | TNBC | - | Methylglyoxal | 0.691 | uM | 13201.184 | 0.9765 | 0.9645 | 1.3314 | |||
| SUM229PE | TNBC | - | Methylglyoxal | 3.46 | uM | 13201.184 | 0.9904 | 0.9855 | 1.3314 | |||
| SUM229PE | TNBC | - | Methylglyoxal | 17.3 | uM | 13201.184 | 0.9599 | 0.9394 | 1.3314 | |||
| SUM229PE | TNBC | - | Methylglyoxal | 86.4 | uM | 13201.184 | 0.9881 | 0.9821 | 1.3314 | |||
| SUM229PE | TNBC | - | Methylglyoxal | 432 | uM | 13201.184 | 0.8655 | 0.7944 | 1.3314 | |||
| SUM229PE | TNBC | - | Methylglyoxal | 2160 | uM | 13201.184 | 0.0087 | -0.9432 | 1.3314 | |||
| SUM229PE | TNBC | - | Methylglyoxal | 10800 | uM | 13201.184 | 0.0108 | -0.9333 | 1.3314 | |||
| SUM229PE | TNBC | - | Methylglyoxal | 54000 | uM | 13201.184 | 0.0070 | -0.9518 | 1.3314 | |||
| SUM52PE | HR+ | Luminal | Methylglyoxal | 0.138 | uM | 13651.184 | 1.0165 | 1.0446 | 0.7406 | |||
| SUM52PE | HR+ | Luminal | Methylglyoxal | 0.691 | uM | 13651.184 | 0.8171 | 0.5225 | 0.7406 | |||
| SUM52PE | HR+ | Luminal | Methylglyoxal | 3.46 | uM | 13651.184 | 0.8951 | 0.7220 | 0.7406 | |||
| SUM52PE | HR+ | Luminal | Methylglyoxal | 17.3 | uM | 13651.184 | 0.8313 | 0.5584 | 0.7406 | |||
| SUM52PE | HR+ | Luminal | Methylglyoxal | 86.4 | uM | 13651.184 | 0.5308 | -0.1495 | 0.7406 | |||
| SUM52PE | HR+ | Luminal | Methylglyoxal | 432 | uM | 13651.184 | 0.6326 | 0.0777 | 0.7406 | |||
| SUM52PE | HR+ | Luminal | Methylglyoxal | 2160 | uM | 13651.184 | 0.1705 | -0.8165 | 0.7406 | |||
| SUM52PE | HR+ | Luminal | Methylglyoxal | 10800 | uM | 13651.184 | 0.2617 | -0.6727 | 0.7406 |