Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | Methylglyoxal | 17.3 | uM | 13173.184 | 0.9722 | 0.9276 | 0.7656 | |||
| HCC1428 | HR+ | Luminal | Methylglyoxal | 86.4 | uM | 13173.184 | 0.9616 | 0.9002 | 0.7656 | |||
| HCC1428 | HR+ | Luminal | Methylglyoxal | 432 | uM | 13173.184 | 0.9282 | 0.8146 | 0.7656 | |||
| HCC1428 | HR+ | Luminal | Methylglyoxal | 2160 | uM | 13173.184 | 0.7562 | 0.3885 | 0.7656 | |||
| HCC1428 | HR+ | Luminal | Methylglyoxal | 10800 | uM | 13173.184 | 0.2879 | -0.6067 | 0.7656 | |||
| HCC1428 | HR+ | Luminal | Methylglyoxal | 54000 | uM | 13173.184 | 0.0095 | -0.9955 | 0.7656 | |||
| HCC1569 | HER2amp | Basal A | Methylglyoxal | 0.138 | uM | 13038.184 | 0.9900 | 0.9820 | 1.1106 | |||
| HCC1569 | HER2amp | Basal A | Methylglyoxal | 0.691 | uM | 13038.184 | 0.9965 | 0.9937 | 1.1106 | |||
| HCC1569 | HER2amp | Basal A | Methylglyoxal | 3.46 | uM | 13038.184 | 1.0470 | 1.0844 | 1.1106 | |||
| HCC1569 | HER2amp | Basal A | Methylglyoxal | 17.3 | uM | 13038.184 | 0.9514 | 0.9123 | 1.1106 | |||
| HCC1569 | HER2amp | Basal A | Methylglyoxal | 86.4 | uM | 13038.184 | 1.0401 | 1.0721 | 1.1106 | |||
| HCC1569 | HER2amp | Basal A | Methylglyoxal | 432 | uM | 13038.184 | 0.9644 | 0.9357 | 1.1106 | |||
| HCC1569 | HER2amp | Basal A | Methylglyoxal | 2160 | uM | 13038.184 | 0.2655 | -0.3941 | 1.1106 | |||
| HCC1569 | HER2amp | Basal A | Methylglyoxal | 10800 | uM | 13038.184 | 0.0080 | -0.9740 | 1.1106 | |||
| HCC1569 | HER2amp | Basal A | Methylglyoxal | 54000 | uM | 13038.184 | 0.0049 | -0.9835 | 1.1106 | |||
| HCC1569 | HER2amp | Basal A | Methylglyoxal | 0.138 | uM | 13500.184 | 0.9300 | 0.9128 | 1.6266 | |||
| HCC1569 | HER2amp | Basal A | Methylglyoxal | 0.691 | uM | 13500.184 | 1.0200 | 1.0245 | 1.6266 | |||
| HCC1569 | HER2amp | Basal A | Methylglyoxal | 3.46 | uM | 13500.184 | 0.9603 | 0.9508 | 1.6266 | |||
| HCC1569 | HER2amp | Basal A | Methylglyoxal | 17.3 | uM | 13500.184 | 0.9787 | 0.9737 | 1.6266 | |||
| HCC1569 | HER2amp | Basal A | Methylglyoxal | 86.4 | uM | 13500.184 | 1.0017 | 1.0020 | 1.6266 | |||
| HCC1569 | HER2amp | Basal A | Methylglyoxal | 432 | uM | 13500.184 | 0.8624 | 0.8260 | 1.6266 | |||
| HCC1569 | HER2amp | Basal A | Methylglyoxal | 2160 | uM | 13500.184 | 0.2875 | -0.0705 | 1.6266 | |||
| HCC1569 | HER2amp | Basal A | Methylglyoxal | 10800 | uM | 13500.184 | 0.0415 | -0.7173 | 1.6266 | |||
| HCC1569 | HER2amp | Basal A | Methylglyoxal | 54000 | uM | 13500.184 | 0.0049 | -0.9238 | 1.6266 | |||
| HCC1806 | TNBC | Basal A | Methylglyoxal | 0.138 | uM | 13543.184 | 0.9121 | 0.8842 | 1.5433 |