Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | Methylglyoxal | 54000 | uM | 13651.184 | 0.8295 | 0.5539 | 0.7406 | |||
| T47D | HR+ | Luminal | Methylglyoxal | 0.138 | uM | 13623.184 | 0.9217 | 0.8599 | 1.1220 | |||
| T47D | HR+ | Luminal | Methylglyoxal | 0.691 | uM | 13623.184 | 0.9487 | 0.9082 | 1.1220 | |||
| T47D | HR+ | Luminal | Methylglyoxal | 3.46 | uM | 13623.184 | 0.9051 | 0.8299 | 1.1220 | |||
| T47D | HR+ | Luminal | Methylglyoxal | 17.3 | uM | 13623.184 | 0.9309 | 0.8764 | 1.1220 | |||
| T47D | HR+ | Luminal | Methylglyoxal | 86.4 | uM | 13623.184 | 0.9007 | 0.8221 | 1.1220 | |||
| T47D | HR+ | Luminal | Methylglyoxal | 432 | uM | 13623.184 | 0.9000 | 0.8208 | 1.1220 | |||
| T47D | HR+ | Luminal | Methylglyoxal | 2160 | uM | 13623.184 | 0.3261 | -0.2633 | 1.1220 | |||
| T47D | HR+ | Luminal | Methylglyoxal | 10800 | uM | 13623.184 | 0.0760 | -0.7988 | 1.1220 | |||
| T47D | HR+ | Luminal | Methylglyoxal | 54000 | uM | 13623.184 | 0.8474 | 0.7256 | 1.1220 | |||
| T47DKBLUC | Unknown | Unknown | Methylglyoxal | 0.138 | uM | 13070.184 | 0.9500 | 0.8850 | 0.8653 | |||
| T47DKBLUC | Unknown | Unknown | Methylglyoxal | 0.691 | uM | 13070.184 | 0.9599 | 0.9075 | 0.8653 | |||
| T47DKBLUC | Unknown | Unknown | Methylglyoxal | 3.46 | uM | 13070.184 | 0.9707 | 0.9325 | 0.8653 | |||
| T47DKBLUC | Unknown | Unknown | Methylglyoxal | 17.3 | uM | 13070.184 | 0.9629 | 0.9145 | 0.8653 | |||
| T47DKBLUC | Unknown | Unknown | Methylglyoxal | 86.4 | uM | 13070.184 | 0.9709 | 0.9328 | 0.8653 | |||
| T47DKBLUC | Unknown | Unknown | Methylglyoxal | 432 | uM | 13070.184 | 0.9546 | 0.8954 | 0.8653 | |||
| T47DKBLUC | Unknown | Unknown | Methylglyoxal | 2160 | uM | 13070.184 | 0.5975 | 0.1031 | 0.8653 | |||
| T47DKBLUC | Unknown | Unknown | Methylglyoxal | 10800 | uM | 13070.184 | 0.0309 | -0.9640 | 0.8653 | |||
| T47DKBLUC | Unknown | Unknown | Methylglyoxal | 54000 | uM | 13070.184 | 0.0081 | -0.9924 | 0.8653 | |||
| UACC-812 | HER2amp | Luminal | Methylglyoxal | 0.138 | uM | 13078.184 | 0.9596 | 0.8822 | 0.6800 | |||
| UACC-812 | HER2amp | Luminal | Methylglyoxal | 0.691 | uM | 13078.184 | 0.9433 | 0.8355 | 0.6800 | |||
| UACC-812 | HER2amp | Luminal | Methylglyoxal | 3.46 | uM | 13078.184 | 0.9704 | 0.9135 | 0.6800 | |||
| UACC-812 | HER2amp | Luminal | Methylglyoxal | 17.3 | uM | 13078.184 | 0.9356 | 0.8135 | 0.6800 | |||
| UACC-812 | HER2amp | Luminal | Methylglyoxal | 86.4 | uM | 13078.184 | 0.9553 | 0.8698 | 0.6800 | |||
| UACC-812 | HER2amp | Luminal | Methylglyoxal | 432 | uM | 13078.184 | 0.9311 | 0.8007 | 0.6800 |