Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HER2amp | Luminal | Methylglyoxal | 432 | uM | 13615.184 | 0.8737 | 0.7853 | 1.1889 | |||
| SK-BR-3 | HER2amp | Luminal | Methylglyoxal | 2160 | uM | 13615.184 | 0.1362 | -0.6262 | 1.1889 | |||
| SK-BR-3 | HER2amp | Luminal | Methylglyoxal | 10800 | uM | 13615.184 | 0.2345 | -0.4094 | 1.1889 | |||
| SK-BR-3 | HER2amp | Luminal | Methylglyoxal | 54000 | uM | 13615.184 | 0.8147 | 0.6832 | 1.1889 | |||
| SUM1315MO2 | TNBC | Basal B | Methylglyoxal | 0.138 | uM | 13197.184 | 0.9926 | 0.9732 | 0.5530 | |||
| SUM1315MO2 | TNBC | Basal B | Methylglyoxal | 0.691 | uM | 13197.184 | 0.9680 | 0.8857 | 0.5530 | |||
| SUM1315MO2 | TNBC | Basal B | Methylglyoxal | 3.46 | uM | 13197.184 | 0.9998 | 0.9993 | 0.5530 | |||
| SUM1315MO2 | TNBC | Basal B | Methylglyoxal | 17.3 | uM | 13197.184 | 0.9737 | 0.9057 | 0.5530 | |||
| SUM1315MO2 | TNBC | Basal B | Methylglyoxal | 86.4 | uM | 13197.184 | 0.9604 | 0.8589 | 0.5530 | |||
| SUM1315MO2 | TNBC | Basal B | Methylglyoxal | 432 | uM | 13197.184 | 0.8801 | 0.5874 | 0.5530 | |||
| SUM1315MO2 | TNBC | Basal B | Methylglyoxal | 2160 | uM | 13197.184 | 0.3384 | -0.7182 | 0.5530 | |||
| SUM1315MO2 | TNBC | Basal B | Methylglyoxal | 10800 | uM | 13197.184 | 0.1406 | -0.9424 | 0.5530 | |||
| SUM1315MO2 | TNBC | Basal B | Methylglyoxal | 54000 | uM | 13197.184 | 0.0059 | -0.9998 | 0.5530 | |||
| SUM1315MO2 | TNBC | Basal B | Methylglyoxal | 0.138 | uM | 13520.184 | 0.9566 | 0.8725 | 0.6738 | |||
| SUM1315MO2 | TNBC | Basal B | Methylglyoxal | 0.691 | uM | 13520.184 | 1.0272 | 1.0813 | 0.6738 | |||
| SUM1315MO2 | TNBC | Basal B | Methylglyoxal | 3.46 | uM | 13520.184 | 0.9990 | 0.9969 | 0.6738 | |||
| SUM1315MO2 | TNBC | Basal B | Methylglyoxal | 17.3 | uM | 13520.184 | 1.0020 | 1.0059 | 0.6738 | |||
| SUM1315MO2 | TNBC | Basal B | Methylglyoxal | 86.4 | uM | 13520.184 | 1.0104 | 1.0310 | 0.6738 | |||
| SUM1315MO2 | TNBC | Basal B | Methylglyoxal | 432 | uM | 13520.184 | 0.9191 | 0.7645 | 0.6738 | |||
| SUM1315MO2 | TNBC | Basal B | Methylglyoxal | 2160 | uM | 13520.184 | 0.1034 | -0.9310 | 0.6738 | |||
| SUM1315MO2 | TNBC | Basal B | Methylglyoxal | 10800 | uM | 13520.184 | 0.0190 | -0.9944 | 0.6738 | |||
| SUM1315MO2 | TNBC | Basal B | Methylglyoxal | 54000 | uM | 13520.184 | 0.0050 | -0.9992 | 0.6738 | |||
| SUM149PT | TNBC | Basal B | Methylglyoxal | 0.138 | uM | 13123.184 | 0.9649 | 0.8881 | 0.6208 | |||
| SUM149PT | TNBC | Basal B | Methylglyoxal | 0.691 | uM | 13123.184 | 0.9362 | 0.7984 | 0.6208 | |||
| SUM149PT | TNBC | Basal B | Methylglyoxal | 3.46 | uM | 13123.184 | 1.0051 | 1.0164 | 0.6208 |